| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 100 | 12 | 12 | 2 | 4 | 4.78 | .353 | 1.59 | 9.3 | 5.2 | 11.1 | 69.2 | 71 | 40 | 37 | 11 | 40 | 85 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 4.48 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 99 | 11 | 11 | 5 | 2 | 2.89 | .281 | 1.16 | 7.9 | 2.6 | 10.3 | 81.0 | 71 | 26 | 26 | 8 | 23 | 93 | 2 | 0 | 0 | 1 | 7 | 1 | 2 | 2.88 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 32 | 2017 | L | 90 | 11 | 11 | 6 | 5 | 3.32 | .285 | 1.18 | 6.9 | 3.8 | 8.8 | 78.2 | 60 | 29 | 29 | 9 | 33 | 76 | 2 | 0 | 0 | 0 | 8 | 1 | 2 | 3.86 |
| SP | Roark, T.Roark, Tanner # >> | 30 | 2017 | R | 59 | 11 | 11 | 4 | 2 | 4.73 | .325 | 1.43 | 9.3 | 3.6 | 9.2 | 53.1 | 55 | 28 | 28 | 5 | 21 | 54 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 3.43 |
| CL | Albers, M.Albers, Matt >> | 34 | 2017 | R | 95 | 25 | 0 | 4 | 0 | 2.81 | .342 | 1.56 | 10.1 | 4.3 | 11.9 | 25.2 | 28 | 8 | 8 | 2 | 12 | 33 | 0 | 10 | 1 | 0 | 0 | 0 | 0 | 2.84 |
| SU | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 98 | 30 | 0 | 1 | 3 | 4.50 | .303 | 1.28 | 7.5 | 4.0 | 9.0 | 36.0 | 30 | 18 | 18 | 2 | 16 | 36 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.14 |
| RP | Doolittle, S.Doolittle, Sean >> | 30 | 2017 | L | 97 | 35 | 0 | 1 | 2 | 5.46 | .343 | 1.53 | 10.7 | 3.2 | 13.1 | 31.1 | 37 | 19 | 19 | 6 | 11 | 45 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 3.77 |
| RP | Kintzler, B.Kintzler, Brandon >> | 32 | 2017 | R | 62 | 36 | 0 | 2 | 2 | 5.68 | .326 | 1.42 | 9.0 | 4.1 | 9.6 | 31.2 | 31 | 20 | 20 | 5 | 14 | 33 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.42 |
| RP | Perez, O.Perez, Oliver >> | 36 | 2017 | L | 50 | 28 | 0 | 2 | 2 | 4.63 | .360 | 1.66 | 11.6 | 3.3 | 9.3 | 35.0 | 45 | 18 | 18 | 2 | 13 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.89 |