| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 28 | 28 | 11 | 7 | 3.18 | .303 | 1.28 | 7.5 | 4.0 | 7.1 | 218.0 | 182 | 84 | 77 | 22 | 98 | 171 | 7 | 0 | 0 | 2 | 20 | 4 | 3 | 4.15 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 27 | 27 | 5 | 9 | 6.59 | .364 | 1.71 | 11.6 | 3.8 | 5.7 | 154.1 | 199 | 119 | 113 | 25 | 65 | 98 | 2 | 0 | 0 | 1 | 7 | 1 | 3 | 5.12 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 63 | 27 | 27 | 8 | 14 | 4.87 | .317 | 1.36 | 9.3 | 3.0 | 4.5 | 162.2 | 168 | 97 | 88 | 26 | 54 | 81 | 0 | 0 | 0 | 0 | 13 | 4 | 2 | 5.16 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 26 | 26 | 13 | 10 | 4.70 | .312 | 1.32 | 8.7 | 3.2 | 4.1 | 172.1 | 167 | 96 | 90 | 17 | 61 | 79 | 2 | 0 | 0 | 0 | 13 | 6 | 2 | 4.53 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 72 | 0 | 5 | 6 | 4.59 | .318 | 1.37 | 7.4 | 4.9 | 8.2 | 98.0 | 81 | 57 | 50 | 11 | 53 | 89 | 0 | 7 | 0 | 0 | 0 | 3 | 0 | 4.36 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 76 | 64 | 0 | 2 | 5 | 4.68 | .294 | 1.25 | 9.3 | 2.0 | 7.7 | 84.2 | 87 | 46 | 44 | 16 | 19 | 72 | 0 | 8 | 4 | 0 | 0 | 0 | 0 | 4.44 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 51 | 0 | 4 | 4 | 5.13 | .351 | 1.58 | 6.7 | 7.6 | 7.8 | 59.2 | 44 | 34 | 34 | 7 | 50 | 51 | 0 | 9 | 4 | 0 | 0 | 3 | 5 | 5.51 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 15 | 0 | 1 | 2 | 7.89 | .387 | 1.89 | 14.6 | 3.0 | 5.6 | 21.2 | 34 | 19 | 19 | 2 | 7 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.00 |