| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 10 | 10 | 4 | 3 | 3.60 | .242 | 0.93 | 6.6 | 1.8 | 5.3 | 75.0 | 55 | 32 | 30 | 5 | 15 | 44 | 1 | 0 | 0 | 0 | 5 | 2 | 0 | 3.37 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 5 | 5 | 2 | 1 | 5.01 | .297 | 1.27 | 9.6 | 2.0 | 7.9 | 32.1 | 34 | 18 | 18 | 3 | 7 | 28 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.13 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 10 | 10 | 3 | 5 | 3.82 | .296 | 1.25 | 7.6 | 3.6 | 7.5 | 73.0 | 62 | 31 | 31 | 7 | 29 | 61 | 3 | 0 | 0 | 0 | 6 | 1 | 2 | 3.81 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 9 | 9 | 4 | 3 | 4.80 | .331 | 1.47 | 9.6 | 3.6 | 6.9 | 60.0 | 64 | 33 | 32 | 9 | 24 | 46 | 2 | 0 | 0 | 1 | 4 | 1 | 5 | 4.67 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 20 | 0 | 2 | 3 | 4.43 | .315 | 1.33 | 9.0 | 3.2 | 6.3 | 20.1 | 20 | 10 | 10 | 3 | 7 | 14 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.75 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 23 | 0 | 1 | 0 | 3.15 | .286 | 1.15 | 5.9 | 4.5 | 10.8 | 20.0 | 13 | 7 | 7 | 1 | 10 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.90 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 17 | 0 | 0 | 2 | 4.76 | .311 | 1.35 | 9.0 | 3.2 | 7.9 | 17.0 | 17 | 9 | 9 | 3 | 6 | 15 | 0 | 13 | 2 | 0 | 0 | 0 | 0 | 4.59 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 59 | 14 | 0 | 0 | 0 | 4.22 | .347 | 1.59 | 10.8 | 4.5 | 3.6 | 10.2 | 12 | 5 | 5 | 2 | 5 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.30 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 15 | 0 | 1 | 0 | 4.42 | .267 | 1.09 | 7.5 | 2.5 | 11.0 | 18.1 | 15 | 9 | 9 | 2 | 5 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 11 | 0 | 1 | 1 | 2.13 | .333 | 1.50 | 9.8 | 4.5 | 8.3 | 12.2 | 13 | 3 | 3 | 0 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.67 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 14 | 0 | 1 | 1 | 2.03 | .259 | 1.05 | 6.2 | 3.5 | 11.1 | 13.1 | 9 | 3 | 3 | 0 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.69 |