| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 10 | 10 | 6 | 2 | 3.53 | .296 | 1.22 | 7.5 | 3.5 | 7.1 | 71.1 | 59 | 28 | 28 | 10 | 28 | 56 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 4.56 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 10 | 10 | 5 | 4 | 2.63 | .278 | 1.16 | 8.3 | 2.2 | 3.8 | 78.2 | 72 | 27 | 23 | 6 | 19 | 33 | 2 | 0 | 0 | 1 | 7 | 0 | 1 | 3.88 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 10 | 10 | 2 | 4 | 5.58 | .358 | 1.63 | 10.2 | 4.6 | 7.9 | 59.2 | 67 | 40 | 37 | 7 | 30 | 52 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.46 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 20 | 0 | 0 | 4 | 3.68 | .250 | 1.00 | 7.0 | 2.0 | 9.8 | 22.0 | 17 | 9 | 9 | 2 | 5 | 24 | 0 | 11 | 1 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 13 | 0 | 2 | 0 | 5.17 | .356 | 1.66 | 11.4 | 4.2 | 10.8 | 15.2 | 19 | 9 | 9 | 1 | 7 | 18 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.87 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 12 | 0 | 2 | 0 | 1.80 | .262 | 1.07 | 9.0 | 0.6 | 10.2 | 15.0 | 15 | 6 | 3 | 1 | 1 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.80 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 9 | 0 | 1 | 0 | 7.71 | .417 | 2.14 | 12.9 | 6.4 | 5.1 | 7.0 | 10 | 7 | 6 | 1 | 5 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.86 |