| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 29 | 29 | 8 | 16 | 5.80 | .342 | 1.55 | 10.2 | 3.8 | 8.0 | 172.1 | 194 | 116 | 111 | 24 | 73 | 152 | 3 | 0 | 0 | 0 | 13 | 2 | 4 | 4.35 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 28 | 28 | 12 | 13 | 3.67 | .292 | 1.21 | 8.6 | 2.3 | 5.1 | 196.0 | 187 | 95 | 80 | 18 | 50 | 111 | 5 | 0 | 0 | 1 | 17 | 5 | 1 | 3.90 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 28 | 28 | 11 | 7 | 3.58 | .291 | 1.20 | 8.0 | 2.8 | 5.2 | 181.0 | 161 | 87 | 72 | 16 | 57 | 104 | 3 | 0 | 0 | 1 | 16 | 5 | 1 | 4.03 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 28 | 28 | 13 | 10 | 3.89 | .314 | 1.35 | 9.1 | 3.0 | 5.4 | 203.2 | 206 | 95 | 88 | 29 | 68 | 122 | 7 | 0 | 0 | 1 | 16 | 6 | 3 | 4.75 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 42 | 0 | 0 | 2 | 3.23 | .282 | 1.18 | 8.3 | 2.3 | 9.0 | 39.0 | 36 | 15 | 14 | 3 | 10 | 39 | 0 | 33 | 5 | 0 | 0 | 0 | 1 | 2.77 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 36 | 0 | 4 | 0 | 3.51 | .286 | 1.20 | 7.6 | 3.3 | 7.1 | 33.1 | 28 | 16 | 13 | 4 | 12 | 26 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.09 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 25 | 0 | 2 | 2 | 6.23 | .322 | 1.38 | 9.0 | 3.5 | 8.7 | 26.0 | 26 | 19 | 18 | 6 | 10 | 25 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 5.35 |