| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 10 | 10 | 5 | 4 | 4.87 | .312 | 1.33 | 10.1 | 2.0 | 7.1 | 68.1 | 76 | 42 | 37 | 11 | 15 | 54 | 1 | 0 | 0 | 0 | 4 | 2 | 3 | 4.26 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 10 | 10 | 5 | 2 | 4.76 | .315 | 1.30 | 7.0 | 4.8 | 6.4 | 62.1 | 48 | 35 | 33 | 5 | 33 | 44 | 0 | 0 | 0 | 0 | 4 | 5 | 1 | 4.47 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 10 | 10 | 2 | 4 | 4.76 | .340 | 1.49 | 9.8 | 3.6 | 5.5 | 70.0 | 76 | 39 | 37 | 9 | 28 | 43 | 1 | 0 | 0 | 0 | 4 | 4 | 1 | 4.81 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 10 | 10 | 2 | 4 | 4.63 | .357 | 1.65 | 9.8 | 5.1 | 7.9 | 56.1 | 61 | 34 | 29 | 5 | 32 | 49 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.18 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 9 | 9 | 3 | 2 | 4.57 | .342 | 1.56 | 10.9 | 3.1 | 6.6 | 61.0 | 74 | 32 | 31 | 8 | 21 | 45 | 2 | 0 | 0 | 0 | 4 | 0 | 2 | 4.26 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 17 | 0 | 3 | 1 | 3.79 | .219 | 0.84 | 5.2 | 2.4 | 10.4 | 19.0 | 11 | 8 | 8 | 5 | 5 | 22 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 4.89 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 23 | 0 | 0 | 3 | 2.08 | .339 | 1.50 | 8.3 | 5.2 | 9.3 | 26.0 | 24 | 8 | 6 | 4 | 15 | 27 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.77 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 25 | 0 | 0 | 1 | 6.75 | .327 | 1.33 | 8.3 | 3.8 | 7.5 | 24.0 | 22 | 19 | 18 | 5 | 10 | 20 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 5.67 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 29 | 0 | 0 | 0 | 2.12 | .292 | 1.18 | 6.4 | 4.2 | 9.5 | 17.0 | 12 | 6 | 4 | 1 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.24 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 21 | 0 | 2 | 0 | 4.24 | .286 | 1.16 | 8.2 | 2.3 | 6.7 | 23.1 | 21 | 11 | 11 | 3 | 6 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.13 |