| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 86 | 12 | 12 | 3 | 6 | 5.84 | .300 | 1.26 | 9.6 | 1.8 | 10.2 | 77.0 | 82 | 53 | 50 | 17 | 15 | 87 | 1 | 0 | 0 | 0 | 4 | 2 | 0 | 4.27 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 12 | 12 | 7 | 1 | 4.24 | .318 | 1.39 | 9.7 | 2.8 | 5.2 | 74.1 | 80 | 37 | 35 | 9 | 23 | 43 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 4.39 |
| SP | Williams, W.Williams, Woody # >> | 36 | 2002 | R | 79 | 12 | 12 | 7 | 4 | 5.43 | .324 | 1.36 | 9.9 | 2.5 | 7.0 | 69.2 | 76 | 44 | 42 | 12 | 19 | 54 | 0 | 0 | 0 | 0 | 5 | 5 | 2 | 4.74 |
| SP | Alvarez, W.Alvarez, Wilson # >> | 33 | 2003 | L | 74 | 11 | 11 | 1 | 5 | 4.91 | .341 | 1.51 | 11.1 | 2.7 | 5.2 | 47.2 | 58 | 27 | 26 | 4 | 14 | 27 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 3.98 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 67 | 11 | 11 | 8 | 3 | 4.63 | .301 | 1.25 | 8.6 | 2.6 | 5.3 | 72.0 | 69 | 37 | 37 | 10 | 21 | 42 | 1 | 0 | 0 | 0 | 7 | 3 | 2 | 4.64 |
| SU | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 23 | 0 | 0 | 0 | 4.18 | .324 | 1.39 | 10.2 | 2.7 | 8.6 | 23.2 | 26 | 11 | 11 | 3 | 7 | 22 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 3.83 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 73 | 34 | 0 | 1 | 0 | 6.00 | .379 | 1.83 | 9.0 | 7.5 | 11.3 | 24.0 | 24 | 16 | 16 | 3 | 20 | 30 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.63 |
| RP | Perez, R.Perez, Rafael # >> | 25 | 2007 | L | 65 | 31 | 0 | 1 | 1 | 6.32 | .361 | 1.60 | 9.9 | 4.6 | 8.7 | 31.1 | 34 | 23 | 22 | 3 | 16 | 30 | 0 | 3 | 0 | 0 | 0 | 3 | 7 | 4.16 |