| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 25 | 25 | 12 | 9 | 4.06 | .285 | 1.17 | 7.9 | 2.6 | 9.4 | 157.1 | 138 | 74 | 71 | 27 | 46 | 164 | 2 | 0 | 0 | 2 | 15 | 4 | 7 | 4.10 |
| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 88 | 24 | 24 | 8 | 9 | 6.01 | .349 | 1.59 | 10.9 | 3.5 | 9.2 | 127.1 | 154 | 89 | 85 | 33 | 49 | 130 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 5.54 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 76 | 23 | 23 | 5 | 8 | 5.94 | .334 | 1.50 | 9.9 | 3.7 | 10.0 | 113.2 | 124 | 76 | 75 | 18 | 46 | 125 | 1 | 0 | 0 | 0 | 7 | 1 | 3 | 4.11 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 79 | 59 | 0 | 4 | 2 | 3.07 | .329 | 1.43 | 6.9 | 6.0 | 10.5 | 73.1 | 56 | 25 | 25 | 8 | 49 | 85 | 0 | 7 | 1 | 0 | 0 | 3 | 2 | 4.23 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 66 | 43 | 0 | 2 | 0 | 4.25 | .271 | 1.09 | 7.0 | 2.9 | 5.8 | 53.0 | 41 | 25 | 25 | 14 | 17 | 34 | 0 | 7 | 1 | 0 | 0 | 1 | 1 | 6.17 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 70 | 31 | 0 | 3 | 1 | 5.45 | .329 | 1.41 | 9.3 | 3.7 | 8.2 | 34.2 | 35 | 21 | 21 | 2 | 14 | 31 | 0 | 2 | 0 | 0 | 0 | 2 | 5 | 3.35 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 21 | 2 | 1 | 4 | 6.15 | .335 | 1.46 | 9.7 | 3.5 | 4.6 | 41.0 | 44 | 29 | 28 | 8 | 16 | 21 | 0 | 1 | 2 | 0 | 2 | 2 | 1 | 5.83 |