| SP | Schilling, C.Schilling, Curt # >> | 36 | 2002 | R | 93 | 15 | 15 | 8 | 5 | 2.60 | .252 | 1.00 | 6.8 | 2.3 | 9.9 | 124.2 | 93 | 36 | 36 | 8 | 32 | 137 | 5 | 0 | 0 | 1 | 13 | 1 | 1 | 2.43 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 69 | 15 | 15 | 5 | 6 | 5.57 | .336 | 1.48 | 9.6 | 3.8 | 5.7 | 85.2 | 91 | 55 | 53 | 28 | 36 | 54 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 7.39 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 15 | 15 | 1 | 7 | 7.11 | .368 | 1.71 | 11.3 | 4.2 | 6.9 | 82.1 | 103 | 66 | 65 | 17 | 38 | 63 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 5.66 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 16 | 15 | 5 | 8 | 6.04 | .349 | 1.59 | 10.4 | 3.9 | 6.7 | 85.0 | 98 | 60 | 57 | 15 | 37 | 63 | 0 | 0 | 0 | 0 | 7 | 2 | 5 | 5.19 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 75 | 47 | 0 | 1 | 3 | 6.30 | .324 | 1.40 | 10.6 | 2.0 | 9.9 | 50.0 | 59 | 35 | 35 | 12 | 11 | 55 | 0 | 10 | 4 | 0 | 0 | 2 | 0 | 4.70 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 54 | 40 | 0 | 3 | 0 | 3.93 | .318 | 1.37 | 9.0 | 3.4 | 9.3 | 34.1 | 34 | 17 | 15 | 9 | 13 | 35 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 5.62 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 38 | 28 | 0 | 1 | 3 | 4.66 | .320 | 1.31 | 7.4 | 4.3 | 6.2 | 29.0 | 24 | 16 | 15 | 5 | 14 | 20 | 0 | 5 | 1 | 0 | 0 | 3 | 3 | 5.62 |
| RP | Cordero, F.Cordero, Francisco >> | 32 | 2007 | R | 26 | 19 | 0 | 1 | 1 | 5.23 | .326 | 1.40 | 9.5 | 3.6 | 8.6 | 20.2 | 21 | 13 | 12 | 3 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.40 |