| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 36 | 36 | 5 | 8 | 3.68 | .288 | 1.18 | 7.3 | 3.4 | 9.1 | 171.1 | 138 | 70 | 70 | 17 | 65 | 172 | 0 | 0 | 0 | 0 | 5 | 5 | 6 | 3.51 |
| SP | Halladay, R.Halladay, Roy # >> | 28 | 2005 | R | 86 | 34 | 34 | 14 | 11 | 4.59 | .290 | 1.19 | 8.9 | 1.8 | 6.3 | 239.1 | 237 | 128 | 122 | 45 | 47 | 167 | 6 | 0 | 0 | 1 | 13 | 9 | 1 | 4.75 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 33 | 33 | 10 | 12 | 4.77 | .318 | 1.39 | 9.4 | 3.1 | 6.8 | 203.2 | 213 | 113 | 108 | 32 | 70 | 154 | 1 | 0 | 0 | 1 | 14 | 2 | 1 | 4.60 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 65 | 33 | 33 | 9 | 10 | 4.78 | .337 | 1.49 | 9.6 | 3.9 | 6.6 | 182.2 | 194 | 103 | 97 | 23 | 79 | 133 | 1 | 0 | 0 | 1 | 13 | 6 | 8 | 4.58 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 91 | 0 | 11 | 8 | 3.41 | .297 | 1.24 | 7.0 | 4.2 | 9.5 | 121.1 | 94 | 46 | 46 | 13 | 57 | 128 | 0 | 7 | 5 | 0 | 0 | 3 | 2 | 3.77 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 63 | 90 | 0 | 9 | 3 | 4.03 | .338 | 1.48 | 10.4 | 3.0 | 7.5 | 111.2 | 128 | 50 | 50 | 21 | 37 | 92 | 0 | 14 | 3 | 0 | 0 | 6 | 5 | 4.96 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 45 | 75 | 0 | 5 | 4 | 5.12 | .301 | 1.25 | 8.9 | 2.4 | 6.5 | 82.2 | 81 | 47 | 47 | 22 | 22 | 59 | 0 | 13 | 1 | 0 | 0 | 4 | 3 | 6.00 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 36 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 48 | 54 | 0 | 5 | 8 | 6.80 | .378 | 1.78 | 12.3 | 3.8 | 5.5 | 83.1 | 113 | 72 | 63 | 13 | 35 | 51 | 0 | 10 | 2 | 0 | 0 | 4 | 6 | 5.22 |