| SP | Schmidt, J.Schmidt, Jason † >> | 30 | 2003 | R | 99 | 35 | 35 | 17 | 10 | 4.20 | .284 | 1.15 | 7.8 | 2.6 | 9.0 | 261.1 | 225 | 124 | 122 | 37 | 75 | 261 | 9 | 0 | 0 | 3 | 19 | 11 | 3 | 3.83 |
| SP | Weaver, J.Weaver, Jered # >> | 24 | 2006 | R | 83 | 33 | 33 | 17 | 9 | 4.17 | .280 | 1.14 | 7.8 | 2.5 | 7.7 | 231.0 | 199 | 111 | 107 | 22 | 65 | 197 | 2 | 0 | 0 | 1 | 19 | 5 | 5 | 3.44 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 32 | 32 | 14 | 13 | 5.89 | .360 | 1.65 | 10.0 | 4.9 | 7.3 | 195.2 | 216 | 136 | 128 | 43 | 106 | 159 | 1 | 0 | 0 | 0 | 14 | 8 | 10 | 5.99 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 47 | 31 | 31 | 9 | 14 | 6.36 | .361 | 1.65 | 11.9 | 3.0 | 6.9 | 194.0 | 256 | 139 | 137 | 40 | 65 | 149 | 1 | 0 | 0 | 1 | 6 | 8 | 2 | 5.27 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 84 | 73 | 0 | 2 | 3 | 3.43 | .326 | 1.43 | 6.7 | 6.2 | 9.4 | 81.1 | 60 | 33 | 31 | 9 | 56 | 85 | 0 | 14 | 6 | 0 | 0 | 2 | 8 | 4.49 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 48 | 0 | 4 | 1 | 3.02 | .281 | 1.12 | 8.0 | 2.2 | 11.4 | 53.2 | 47 | 18 | 18 | 4 | 13 | 67 | 0 | 7 | 1 | 0 | 0 | 3 | 0 | 2.36 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 42 | 0 | 5 | 3 | 3.28 | .327 | 1.44 | 8.6 | 4.5 | 5.9 | 46.2 | 44 | 17 | 17 | 5 | 23 | 30 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.67 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 39 | 35 | 0 | 2 | 1 | 3.40 | .246 | 0.93 | 6.8 | 1.6 | 8.0 | 45.0 | 34 | 17 | 17 | 6 | 8 | 40 | 0 | 4 | 2 | 0 | 0 | 2 | 4 | 3.62 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 11 | 0 | 2 | 0 | 3.12 | .307 | 1.33 | 5.8 | 6.4 | 10.6 | 17.1 | 11 | 7 | 6 | 0 | 12 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.76 |