| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 11 | 11 | 6 | 4 | 2.34 | .221 | 0.85 | 4.9 | 2.8 | 10.3 | 84.2 | 46 | 22 | 22 | 7 | 26 | 96 | 4 | 0 | 0 | 2 | 8 | 0 | 0 | 2.73 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 86 | 10 | 10 | 4 | 3 | 3.95 | .281 | 1.13 | 7.7 | 2.6 | 7.5 | 70.2 | 60 | 31 | 31 | 14 | 20 | 58 | 2 | 0 | 0 | 0 | 6 | 3 | 0 | 4.93 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 79 | 10 | 10 | 0 | 6 | 9.73 | .425 | 2.14 | 12.6 | 6.6 | 7.8 | 37.0 | 52 | 43 | 40 | 9 | 27 | 32 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 6.86 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 10 | 10 | 4 | 2 | 4.39 | .333 | 1.50 | 9.8 | 3.7 | 4.8 | 53.1 | 58 | 28 | 26 | 10 | 22 | 28 | 1 | 0 | 0 | 0 | 5 | 0 | 1 | 5.64 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 26 | 0 | 1 | 3 | 3.98 | .247 | 0.96 | 6.8 | 2.0 | 8.3 | 40.2 | 30 | 18 | 18 | 3 | 9 | 37 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.88 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 22 | 0 | 2 | 0 | 10.88 | .427 | 2.19 | 16.4 | 3.7 | 12.3 | 22.1 | 40 | 27 | 27 | 10 | 9 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 7.55 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 68 | 20 | 0 | 0 | 1 | 6.14 | .389 | 1.82 | 10.6 | 5.7 | 8.6 | 22.0 | 26 | 15 | 15 | 4 | 14 | 21 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.64 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 71 | 16 | 0 | 2 | 2 | 7.18 | .373 | 1.75 | 9.7 | 6.2 | 9.0 | 26.1 | 28 | 21 | 21 | 8 | 18 | 26 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 7.19 |