| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 34 | 34 | 16 | 12 | 2.77 | .282 | 1.14 | 7.1 | 3.2 | 9.0 | 246.2 | 193 | 82 | 76 | 13 | 88 | 247 | 4 | 0 | 0 | 2 | 25 | 9 | 3 | 2.86 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 33 | 32 | 8 | 14 | 5.91 | .330 | 1.46 | 10.4 | 2.9 | 6.5 | 179.2 | 206 | 118 | 118 | 42 | 57 | 129 | 0 | 0 | 0 | 0 | 13 | 2 | 4 | 5.60 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 57 | 31 | 31 | 9 | 10 | 6.51 | .341 | 1.51 | 10.8 | 2.9 | 6.4 | 179.2 | 215 | 132 | 130 | 32 | 57 | 128 | 1 | 0 | 0 | 1 | 10 | 7 | 5 | 4.97 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 93 | 0 | 5 | 4 | 3.86 | .325 | 1.38 | 8.1 | 4.4 | 8.8 | 102.2 | 92 | 45 | 44 | 14 | 50 | 100 | 0 | 3 | 4 | 0 | 0 | 6 | 7 | 4.47 |
| CL | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 96 | 79 | 0 | 6 | 9 | 3.24 | .267 | 1.05 | 7.7 | 1.8 | 8.4 | 91.2 | 78 | 35 | 33 | 14 | 18 | 85 | 0 | 35 | 3 | 0 | 0 | 4 | 1 | 3.86 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 65 | 0 | 4 | 4 | 4.34 | .313 | 1.34 | 8.1 | 4.0 | 10.2 | 74.2 | 67 | 36 | 36 | 16 | 33 | 84 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 4.96 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 59 | 59 | 0 | 2 | 2 | 3.58 | .269 | 1.10 | 7.6 | 2.4 | 10.5 | 65.1 | 55 | 26 | 26 | 13 | 17 | 76 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.05 |