| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 6 | 12 | 4.36 | .302 | 1.26 | 8.8 | 2.5 | 10.1 | 128.0 | 125 | 66 | 62 | 27 | 36 | 143 | 1 | 0 | 0 | 0 | 10 | 5 | 0 | 4.47 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 23 | 23 | 7 | 9 | 5.27 | .325 | 1.39 | 9.2 | 3.4 | 8.5 | 136.2 | 139 | 84 | 80 | 24 | 51 | 129 | 0 | 0 | 0 | 0 | 8 | 7 | 1 | 4.68 |
| SP | McClanahan, S.McClanahan, Shane # >> | 25 | 2022 | L | 89 | 21 | 21 | 4 | 14 | 6.91 | .366 | 1.71 | 11.5 | 4.0 | 8.2 | 113.1 | 144 | 88 | 87 | 28 | 50 | 103 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 5.78 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 88 | 21 | 21 | 5 | 9 | 5.11 | .328 | 1.44 | 8.4 | 4.6 | 8.8 | 116.1 | 108 | 67 | 66 | 14 | 59 | 114 | 0 | 0 | 0 | 0 | 11 | 3 | 7 | 4.21 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 69 | 0 | 2 | 2 | 2.72 | .260 | 1.03 | 5.3 | 3.9 | 10.2 | 76.0 | 45 | 23 | 23 | 5 | 33 | 86 | 0 | 5 | 0 | 0 | 0 | 2 | 1 | 2.97 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 60 | 50 | 0 | 2 | 3 | 3.40 | .326 | 1.45 | 7.4 | 5.8 | 12.1 | 50.1 | 41 | 20 | 19 | 6 | 32 | 67 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 3.80 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 24 | 0 | 3 | 2 | 2.93 | .284 | 1.16 | 6.3 | 4.3 | 10.7 | 27.2 | 19 | 9 | 9 | 2 | 13 | 32 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.15 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 75 | 0 | 5 | 1 | 4.03 | .290 | 1.18 | 6.6 | 4.1 | 9.6 | 60.1 | 44 | 27 | 27 | 11 | 27 | 64 | 0 | 2 | 1 | 0 | 0 | 3 | 3 | 4.75 |