| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 4 | 4 | 3 | 0 | 5.76 | .360 | 1.65 | 9.6 | 5.6 | 3.7 | 29.2 | 31 | 20 | 19 | 5 | 18 | 12 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 6.38 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 3 | 3 | 1 | 0 | 4.58 | .298 | 1.27 | 8.1 | 3.8 | 7.6 | 19.2 | 17 | 11 | 10 | 3 | 8 | 16 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.63 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 10 | 0 | 2 | 1 | 2.13 | .255 | 0.95 | 6.0 | 3.0 | 9.8 | 12.2 | 8 | 3 | 3 | 0 | 4 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.08 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 10 | 0 | 0 | 0 | 2.92 | .315 | 1.38 | 8.3 | 4.5 | 8.3 | 12.1 | 11 | 4 | 4 | 0 | 6 | 11 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 2.67 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 4 | 0 | 1 | 0 | 3.60 | .250 | 1.00 | 9.0 | 0.0 | 7.2 | 5.0 | 5 | 2 | 2 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.40 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 4 | 0 | 1 | 0 | 0.00 | .182 | 0.67 | 4.5 | 1.5 | 9.0 | 6.0 | 3 | 0 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.50 |