| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 4 | 4 | 2 | 2 | 4.38 | .345 | 1.54 | 10.9 | 3.4 | 10.5 | 24.2 | 29 | 14 | 12 | 2 | 9 | 28 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3.00 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 4 | 4 | 1 | 1 | 6.26 | .349 | 1.61 | 8.2 | 6.3 | 5.1 | 23.0 | 21 | 16 | 16 | 4 | 16 | 13 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 6.22 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 4 | 4 | 3 | 1 | 5.59 | .331 | 1.41 | 10.6 | 2.2 | 8.1 | 29.0 | 34 | 18 | 18 | 2 | 7 | 26 | 1 | 0 | 0 | 0 | 1 | 2 | 4 | 3.03 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 10 | 0 | 0 | 0 | 2.77 | .350 | 1.54 | 8.3 | 5.5 | 7.6 | 13.0 | 12 | 7 | 4 | 1 | 8 | 11 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.38 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 11 | 0 | 1 | 0 | 0.59 | .220 | 0.78 | 5.4 | 1.8 | 7.2 | 15.1 | 9 | 1 | 1 | 0 | 3 | 12 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.20 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 3 | 0 | 0 | 1 | 3.86 | .364 | 1.71 | 18.0 | 0.0 | 4.5 | 2.1 | 4 | 3 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |