| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 9 | 9 | 4 | 3 | 5.33 | .323 | 1.37 | 8.1 | 4.2 | 7.5 | 49.0 | 44 | 31 | 29 | 5 | 23 | 41 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 4.24 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 9 | 9 | 5 | 3 | 3.70 | .271 | 1.10 | 8.2 | 1.7 | 4.2 | 58.1 | 53 | 24 | 24 | 4 | 11 | 27 | 3 | 0 | 0 | 0 | 6 | 1 | 0 | 3.59 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 9 | 9 | 5 | 2 | 2.36 | .251 | 0.98 | 6.9 | 2.0 | 4.2 | 68.2 | 52 | 24 | 18 | 7 | 15 | 32 | 1 | 0 | 0 | 0 | 7 | 2 | 1 | 4.15 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 9 | 9 | 1 | 4 | 7.63 | .397 | 1.91 | 12.1 | 5.1 | 3.7 | 46.0 | 62 | 40 | 39 | 7 | 26 | 19 | 0 | 0 | 0 | 0 | 1 | 3 | 2 | 6.04 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 9 | 9 | 4 | 3 | 4.97 | .306 | 1.29 | 8.7 | 3.0 | 8.0 | 54.1 | 52 | 31 | 30 | 6 | 18 | 48 | 3 | 0 | 0 | 1 | 5 | 2 | 0 | 3.78 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 21 | 0 | 1 | 0 | 3.68 | .327 | 1.45 | 8.2 | 4.9 | 11.5 | 22.0 | 20 | 9 | 9 | 3 | 12 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.86 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 20 | 0 | 0 | 1 | 1.42 | .262 | 0.99 | 4.3 | 4.7 | 9.7 | 25.1 | 12 | 5 | 4 | 2 | 13 | 27 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 3.68 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 16 | 0 | 1 | 1 | 1.86 | .284 | 1.19 | 7.1 | 3.8 | 8.1 | 19.1 | 15 | 4 | 4 | 0 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.47 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 13 | 0 | 0 | 1 | 3.18 | .239 | 0.94 | 4.8 | 3.7 | 5.3 | 17.0 | 9 | 6 | 6 | 2 | 7 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.59 |
| RP | Campbell, B.Campbell, Bill >> | 28 | 1976 | R | 2 | 9 | 0 | 0 | 0 | 6.39 | .367 | 1.74 | 12.0 | 4.5 | 6.0 | 12.2 | 16 | 10 | 9 | 0 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.17 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 15 | 0 | 2 | 1 | 0.60 | .118 | 0.40 | 3.0 | 0.6 | 11.4 | 15.0 | 5 | 3 | 1 | 1 | 1 | 19 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 1.53 |