| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 30 | 30 | 11 | 9 | 3.29 | .273 | 1.09 | 7.2 | 2.6 | 9.2 | 194.0 | 156 | 77 | 71 | 27 | 56 | 199 | 1 | 0 | 0 | 0 | 21 | 6 | 0 | 3.72 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 28 | 28 | 8 | 15 | 4.89 | .320 | 1.39 | 10.2 | 2.3 | 5.9 | 186.0 | 210 | 114 | 101 | 30 | 48 | 122 | 6 | 0 | 0 | 0 | 13 | 4 | 2 | 4.62 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 70 | 0 | 3 | 5 | 3.84 | .318 | 1.36 | 7.6 | 4.7 | 8.5 | 84.1 | 71 | 42 | 36 | 4 | 44 | 79 | 0 | 1 | 2 | 0 | 0 | 3 | 1 | 3.42 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 59 | 0 | 6 | 7 | 6.12 | .355 | 1.58 | 9.4 | 4.9 | 7.9 | 64.2 | 67 | 49 | 44 | 9 | 35 | 56 | 0 | 4 | 1 | 0 | 0 | 5 | 0 | 4.95 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 36 | 0 | 0 | 1 | 5.12 | .345 | 1.58 | 9.2 | 5.2 | 8.1 | 38.2 | 39 | 22 | 22 | 8 | 22 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.68 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 35 | 0 | 1 | 1 | 5.02 | .339 | 1.51 | 9.7 | 4.1 | 6.6 | 37.2 | 40 | 21 | 21 | 9 | 17 | 27 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.16 |
| SU | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 57 | 0 | 3 | 3 | 3.44 | .259 | 1.05 | 6.7 | 2.8 | 9.6 | 70.2 | 52 | 28 | 27 | 9 | 22 | 75 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 28 | 0 | 1 | 0 | 2.95 | .333 | 1.42 | 10.0 | 3.0 | 9.3 | 36.2 | 40 | 12 | 12 | 3 | 12 | 37 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 3.28 |