| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 8 | 8 | 3 | 3 | 5.90 | .343 | 1.55 | 11.5 | 2.5 | 8.5 | 50.1 | 64 | 38 | 33 | 7 | 14 | 47 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 3.84 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 9 | 9 | 8 | 1 | 1.98 | .227 | 0.88 | 6.4 | 1.6 | 4.6 | 72.2 | 51 | 16 | 16 | 3 | 13 | 37 | 0 | 0 | 0 | 0 | 8 | 0 | 1 | 3.06 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 9 | 9 | 5 | 2 | 3.29 | .299 | 1.26 | 7.5 | 4.0 | 6.2 | 54.2 | 45 | 20 | 20 | 4 | 24 | 37 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 3.98 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 9 | 9 | 5 | 2 | 3.13 | .299 | 1.22 | 7.3 | 3.7 | 6.9 | 63.1 | 51 | 22 | 22 | 5 | 26 | 48 | 2 | 0 | 0 | 0 | 6 | 4 | 0 | 3.94 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 13 | 0 | 1 | 2 | 2.51 | .204 | 0.77 | 5.8 | 1.3 | 10.9 | 14.1 | 9 | 4 | 4 | 1 | 2 | 17 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1.93 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 7 | 0 | 0 | 1 | 3.24 | .242 | 0.96 | 3.4 | 5.6 | 5.6 | 8.1 | 3 | 4 | 3 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.63 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 7 | 0 | 0 | 1 | 1.93 | .222 | 0.86 | 6.0 | 2.0 | 8.0 | 9.1 | 6 | 2 | 2 | 1 | 2 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.33 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 17 | 0 | 1 | 0 | 2.76 | .258 | 1.04 | 6.2 | 3.4 | 5.1 | 16.1 | 11 | 5 | 5 | 0 | 6 | 9 | 0 | 13 | 1 | 0 | 0 | 0 | 2 | 3.00 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 2 | 1 | 1 | 0 | 1.72 | .242 | 0.89 | 4.2 | 4.2 | 1.8 | 15.2 | 7 | 3 | 3 | 1 | 7 | 3 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5.07 |