| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 98 | 36 | 36 | 13 | 10 | 3.57 | .279 | 1.13 | 8.0 | 2.2 | 8.5 | 232.0 | 207 | 103 | 92 | 29 | 56 | 218 | 1 | 0 | 0 | 1 | 23 | 6 | 5 | 3.55 |
| SP | Rodon, C.Rodon, Carlos # >> | 32 | 2025 | L | 91 | 35 | 35 | 14 | 10 | 2.61 | .280 | 1.14 | 6.9 | 3.4 | 10.2 | 224.0 | 171 | 71 | 65 | 12 | 84 | 254 | 0 | 0 | 0 | 0 | 24 | 6 | 2 | 2.63 |
| SP | Rasmussen, D.Rasmussen, Drew # >> | 29 | 2025 | R | 85 | 34 | 34 | 8 | 10 | 4.56 | .320 | 1.40 | 9.4 | 3.3 | 8.5 | 177.2 | 185 | 95 | 90 | 29 | 64 | 167 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 4.36 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 81 | 33 | 33 | 6 | 9 | 4.74 | .328 | 1.44 | 10.2 | 2.8 | 9.1 | 159.1 | 181 | 94 | 84 | 25 | 49 | 161 | 0 | 0 | 0 | 0 | 5 | 3 | 4 | 4.00 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 79 | 31 | 31 | 6 | 12 | 5.29 | .345 | 1.57 | 10.2 | 4.0 | 7.4 | 161.2 | 183 | 108 | 95 | 37 | 71 | 132 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 5.71 |
| RP | Rodríguez, R.Rodríguez, Randy † >> | 25 | 2025 | R | 94 | 86 | 0 | 10 | 5 | 2.32 | .269 | 1.08 | 7.3 | 2.5 | 11.3 | 132.0 | 107 | 42 | 34 | 9 | 36 | 165 | 0 | 3 | 3 | 0 | 0 | 3 | 3 | 2.27 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 89 | 91 | 0 | 7 | 3 | 2.60 | .279 | 1.14 | 6.8 | 3.4 | 11.8 | 121.1 | 92 | 39 | 35 | 12 | 46 | 158 | 0 | 9 | 5 | 0 | 0 | 3 | 0 | 2.89 |
| RP | Keller, B.Keller, Brad >> | 29 | 2025 | R | 88 | 84 | 0 | 11 | 6 | 3.76 | .295 | 1.23 | 8.2 | 2.9 | 9.4 | 105.1 | 96 | 47 | 44 | 9 | 34 | 110 | 0 | 10 | 3 | 0 | 0 | 2 | 1 | 3.05 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 78 | 61 | 0 | 6 | 6 | 4.76 | .350 | 1.56 | 9.9 | 4.1 | 11.3 | 68.0 | 75 | 41 | 36 | 10 | 31 | 85 | 0 | 8 | 6 | 0 | 0 | 4 | 3 | 3.96 |
| RP | Williams, D.Williams, Devin >> | 30 | 2025 | R | 75 | 55 | 0 | 3 | 2 | 2.11 | .292 | 1.19 | 6.3 | 4.6 | 9.6 | 59.2 | 41 | 14 | 14 | 4 | 30 | 63 | 0 | 10 | 1 | 0 | 0 | 3 | 1 | 3.42 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 59 | 46 | 0 | 4 | 2 | 4.09 | .330 | 1.46 | 9.4 | 4.0 | 8.8 | 50.2 | 52 | 27 | 23 | 5 | 22 | 49 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.72 |
| SP | Priester, Q.Priester, Quinn >> | 24 | 2025 | R | 53 | 15 | 0 | 3 | 3 | 5.76 | .312 | 1.36 | 9.4 | 2.9 | 10.1 | 25.0 | 26 | 16 | 16 | 5 | 8 | 28 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 4.32 |