| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 28 | 28 | 4 | 9 | 5.36 | .349 | 1.59 | 10.8 | 3.6 | 10.1 | 152.2 | 182 | 101 | 91 | 28 | 60 | 170 | 0 | 0 | 0 | 0 | 11 | 4 | 3 | 4.42 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 89 | 28 | 28 | 4 | 12 | 4.71 | .351 | 1.57 | 8.6 | 5.6 | 11.4 | 137.2 | 131 | 78 | 72 | 16 | 85 | 174 | 0 | 0 | 0 | 0 | 4 | 7 | 5 | 3.99 |
| SP | Lodolo, N.Lodolo, Nick >> | 27 | 2025 | L | 78 | 27 | 27 | 9 | 6 | 4.93 | .308 | 1.30 | 9.2 | 2.5 | 10.6 | 149.2 | 153 | 88 | 82 | 17 | 42 | 176 | 0 | 0 | 0 | 0 | 7 | 5 | 2 | 3.07 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 73 | 27 | 27 | 11 | 11 | 5.43 | .329 | 1.42 | 9.5 | 3.3 | 8.4 | 159.0 | 168 | 101 | 96 | 29 | 58 | 149 | 0 | 0 | 0 | 0 | 11 | 8 | 3 | 4.74 |
| SP | Cabrera, E.Cabrera, Edward >> | 27 | 2025 | R | 70 | 30 | 27 | 9 | 10 | 4.90 | .352 | 1.59 | 9.8 | 4.6 | 9.8 | 150.2 | 163 | 96 | 82 | 24 | 77 | 163 | 0 | 1 | 0 | 0 | 5 | 6 | 12 | 4.57 |
| RP | Okert, S.Okert, Steven † >> | 33 | 2025 | L | 96 | 87 | 0 | 14 | 6 | 3.96 | .294 | 1.22 | 8.2 | 2.9 | 10.4 | 120.1 | 109 | 53 | 53 | 11 | 38 | 139 | 0 | 3 | 5 | 0 | 0 | 3 | 0 | 2.90 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 83 | 86 | 0 | 5 | 7 | 4.84 | .309 | 1.33 | 7.9 | 4.1 | 10.7 | 102.1 | 89 | 62 | 55 | 17 | 47 | 121 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 4.21 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 82 | 80 | 0 | 5 | 3 | 5.64 | .363 | 1.61 | 9.7 | 4.7 | 9.9 | 99.0 | 107 | 64 | 62 | 13 | 52 | 109 | 0 | 10 | 1 | 0 | 0 | 10 | 2 | 4.38 |
| RP | Iglesias, R.Iglesias, Raisel >> | 35 | 2025 | R | 78 | 70 | 0 | 3 | 3 | 5.64 | .337 | 1.49 | 9.0 | 4.4 | 9.8 | 81.1 | 81 | 52 | 51 | 17 | 40 | 88 | 0 | 6 | 3 | 0 | 0 | 3 | 0 | 5.15 |