| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 30 | 30 | 10 | 10 | 3.25 | .283 | 1.13 | 7.8 | 2.4 | 10.6 | 202.1 | 175 | 73 | 73 | 19 | 53 | 239 | 1 | 0 | 0 | 1 | 22 | 11 | 2 | 2.81 |
| SP | Brown, H.Brown, Hunter >> | 26 | 2025 | R | 93 | 29 | 29 | 11 | 14 | 3.55 | .297 | 1.25 | 7.4 | 3.8 | 10.4 | 185.0 | 152 | 76 | 73 | 12 | 79 | 213 | 2 | 0 | 0 | 1 | 18 | 4 | 0 | 2.89 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 92 | 29 | 29 | 14 | 6 | 3.87 | .287 | 1.19 | 7.6 | 3.2 | 10.7 | 162.2 | 137 | 70 | 70 | 22 | 57 | 193 | 0 | 0 | 0 | 0 | 10 | 2 | 0 | 3.48 |
| SP | Woods Richardson, S.Woods Richardson, Simeon >> | 24 | 2025 | R | 59 | 32 | 28 | 7 | 10 | 5.04 | .326 | 1.43 | 8.8 | 4.0 | 8.8 | 141.0 | 138 | 84 | 79 | 24 | 63 | 138 | 0 | 2 | 1 | 0 | 5 | 4 | 3 | 4.68 |
| RP | Raley, B.Raley, Brooks >> | 37 | 2025 | L | 97 | 106 | 0 | 4 | 1 | 2.26 | .272 | 1.06 | 6.9 | 2.7 | 10.1 | 95.2 | 73 | 25 | 24 | 6 | 28 | 107 | 0 | 7 | 1 | 0 | 0 | 6 | 0 | 2.64 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 86 | 94 | 0 | 7 | 6 | 3.64 | .305 | 1.26 | 7.8 | 3.7 | 10.7 | 108.2 | 93 | 44 | 44 | 14 | 44 | 128 | 0 | 9 | 4 | 0 | 0 | 6 | 1 | 3.70 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 68 | 81 | 0 | 7 | 4 | 3.53 | .309 | 1.33 | 7.9 | 4.1 | 10.3 | 99.1 | 87 | 39 | 39 | 11 | 45 | 113 | 0 | 7 | 3 | 0 | 0 | 1 | 4 | 3.56 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 67 | 73 | 0 | 2 | 2 | 2.54 | .224 | 0.83 | 5.8 | 1.7 | 7.7 | 88.2 | 57 | 26 | 25 | 5 | 17 | 75 | 0 | 14 | 1 | 0 | 0 | 3 | 0 | 2.72 |
| RP | Finnegan, K.Finnegan, Kyle >> | 33 | 2025 | R | 64 | 51 | 0 | 4 | 6 | 4.33 | .314 | 1.38 | 8.9 | 3.6 | 9.2 | 60.1 | 59 | 29 | 29 | 9 | 24 | 61 | 0 | 7 | 2 | 0 | 0 | 0 | 5 | 4.12 |