| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 64 | 5 | 5 | 1 | 2 | 6.27 | .371 | 1.71 | 8.5 | 7.5 | 10.0 | 18.2 | 17 | 13 | 13 | 2 | 15 | 20 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 4.89 |
| SP | Liriano, F.Liriano, Francisco # >> | 27 | 2010 | L | 56 | 6 | 6 | 3 | 2 | 5.35 | .365 | 1.73 | 10.5 | 5.1 | 6.9 | 35.1 | 41 | 21 | 21 | 5 | 20 | 27 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 5.03 |
| SP | Dempster, R.Dempster, Ryan >> | 33 | 2010 | R | 49 | 5 | 5 | 0 | 4 | 7.09 | .380 | 1.76 | 12.1 | 4.2 | 4.2 | 26.2 | 35 | 21 | 21 | 8 | 12 | 12 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 7.69 |
| RP | Rivera, M.Rivera, Mariano >> | 41 | 2010 | R | 91 | 14 | 0 | 1 | 0 | 2.53 | .281 | 1.17 | 8.6 | 2.1 | 9.4 | 21.1 | 20 | 7 | 6 | 2 | 5 | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.86 |
| RP | Sonnanstine, A.Sonnanstine, Andy >> | 27 | 2010 | R | 4 | 7 | 0 | 0 | 0 | 2.61 | .295 | 1.16 | 9.9 | 0.9 | 9.0 | 10.1 | 11 | 3 | 3 | 1 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.90 |
| SP | Pelfrey, M.Pelfrey, Mike >> | 26 | 2010 | R | 11 | 7 | 0 | 2 | 1 | 0.83 | .253 | 0.92 | 5.6 | 3.0 | 5.1 | 21.2 | 13 | 2 | 2 | 0 | 7 | 12 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.14 |