| SP | Anderson, B.Anderson, Brett # >> | 22 | 2010 | L | 51 | 21 | 21 | 4 | 8 | 3.97 | .310 | 1.33 | 9.1 | 2.9 | 6.5 | 113.1 | 114 | 52 | 50 | 6 | 37 | 81 | 0 | 0 | 0 | 0 | 5 | 2 | 5 | 3.29 |
| SP | Garland, J.Garland, Jon >> | 31 | 2010 | R | 46 | 20 | 20 | 9 | 5 | 3.63 | .318 | 1.39 | 8.1 | 4.4 | 5.9 | 126.1 | 114 | 54 | 51 | 15 | 62 | 83 | 0 | 0 | 0 | 0 | 15 | 1 | 1 | 4.73 |
| SP | Pavano, C.Pavano, Carl >> | 34 | 2010 | R | 43 | 19 | 19 | 6 | 11 | 4.92 | .343 | 1.56 | 11.3 | 2.7 | 5.9 | 115.1 | 145 | 63 | 63 | 14 | 35 | 76 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.20 |
| SP | Cueto, J.Cueto, Johnny >> | 24 | 2010 | R | 38 | 20 | 20 | 5 | 9 | 5.70 | .323 | 1.41 | 9.1 | 3.6 | 6.5 | 109.0 | 110 | 74 | 69 | 21 | 44 | 79 | 1 | 0 | 0 | 0 | 5 | 2 | 2 | 5.32 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 94 | 62 | 0 | 3 | 1 | 2.90 | .251 | 0.99 | 6.5 | 2.5 | 9.3 | 83.2 | 60 | 27 | 27 | 7 | 23 | 86 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.89 |
| RP | Oliver, D.Oliver, Darren >> | 40 | 2010 | L | 47 | 55 | 0 | 3 | 0 | 4.99 | .319 | 1.37 | 9.0 | 3.5 | 8.8 | 57.2 | 57 | 36 | 32 | 6 | 22 | 56 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.67 |
| RP | Storen, D.Storen, Drew >> | 22 | 2010 | R | 32 | 64 | 0 | 5 | 0 | 4.73 | .332 | 1.49 | 9.2 | 4.3 | 6.9 | 59.0 | 60 | 31 | 31 | 9 | 28 | 45 | 0 | 3 | 2 | 0 | 0 | 0 | 4 | 4.88 |
| SP | Pelfrey, M.Pelfrey, Mike >> | 26 | 2010 | R | 11 | 5 | 1 | 0 | 2 | 8.71 | .446 | 2.42 | 16.2 | 6.3 | 6.3 | 10.1 | 18 | 10 | 10 | 0 | 7 | 7 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 3.70 |