| SP | Padilla, V.Padilla, Vicente >> | 33 | 2010 | R | 94 | 21 | 21 | 7 | 3 | 3.26 | .324 | 1.41 | 9.7 | 3.1 | 7.0 | 110.1 | 118 | 42 | 40 | 14 | 38 | 86 | 0 | 0 | 0 | 0 | 6 | 3 | 0 | 4.21 |
| SP | Sanchez, J.Sanchez, Jonathan >> | 28 | 2010 | L | 82 | 21 | 21 | 3 | 6 | 3.53 | .312 | 1.34 | 8.0 | 4.1 | 9.5 | 109.2 | 97 | 44 | 43 | 14 | 50 | 115 | 0 | 0 | 0 | 0 | 5 | 2 | 5 | 3.99 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 25 | 2010 | L | 55 | 20 | 20 | 1 | 10 | 6.95 | .356 | 1.61 | 9.4 | 5.2 | 5.5 | 103.2 | 108 | 84 | 80 | 19 | 59 | 63 | 0 | 0 | 0 | 0 | 5 | 5 | 3 | 6.04 |
| SP | Tomlin, J.Tomlin, Josh # >> | 25 | 2010 | R | 41 | 20 | 20 | 7 | 6 | 4.65 | .309 | 1.32 | 9.1 | 2.8 | 6.0 | 127.2 | 128 | 66 | 66 | 20 | 40 | 84 | 0 | 0 | 0 | 0 | 12 | 3 | 1 | 4.74 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 95 | 53 | 0 | 6 | 4 | 4.23 | .314 | 1.33 | 8.9 | 3.2 | 9.7 | 78.2 | 77 | 39 | 37 | 9 | 28 | 84 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 3.54 |
| RP | Guerrier, M.Guerrier, Matt >> | 32 | 2010 | R | 51 | 54 | 0 | 3 | 7 | 4.46 | .316 | 1.39 | 9.1 | 3.5 | 5.8 | 78.2 | 79 | 43 | 39 | 13 | 30 | 50 | 0 | 0 | 5 | 0 | 0 | 0 | 3 | 5.04 |
| RP | Zambrano, C.Zambrano, Carlos >> | 29 | 2010 | R | 9 | 33 | 0 | 2 | 4 | 4.09 | .350 | 1.62 | 8.7 | 5.9 | 7.0 | 55.0 | 53 | 27 | 25 | 7 | 36 | 43 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 5.05 |
| SP | Santana, E.Santana, Ervin >> | 27 | 2010 | R | 28 | 12 | 0 | 0 | 2 | 4.60 | .390 | 1.91 | 13.2 | 4.8 | 12.6 | 15.2 | 22 | 9 | 8 | 1 | 8 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 2.67 |