| SP | Weaver, J.Weaver, Jered >> | 28 | 2010 | R | 96 | 37 | 37 | 16 | 10 | 3.25 | .278 | 1.14 | 8.4 | 1.8 | 9.5 | 241.0 | 226 | 95 | 87 | 24 | 48 | 255 | 0 | 0 | 0 | 0 | 24 | 4 | 2 | 2.83 |
| SP | Cahill, T.Cahill, Trevor >> | 22 | 2010 | R | 84 | 35 | 35 | 19 | 10 | 2.94 | .294 | 1.22 | 7.6 | 3.4 | 5.9 | 232.2 | 196 | 79 | 76 | 20 | 88 | 153 | 0 | 0 | 0 | 0 | 26 | 7 | 6 | 4.03 |
| SP | Wilson, C.Wilson, C.J. † >> | 30 | 2010 | L | 74 | 34 | 34 | 12 | 12 | 3.61 | .308 | 1.30 | 8.1 | 3.6 | 6.0 | 226.2 | 204 | 94 | 91 | 13 | 91 | 151 | 0 | 0 | 0 | 0 | 21 | 8 | 7 | 3.73 |
| SP | Dickey, R.Dickey, R.A. # >> | 36 | 2010 | R | 58 | 33 | 33 | 11 | 10 | 4.58 | .319 | 1.37 | 9.4 | 3.0 | 6.7 | 194.2 | 202 | 100 | 99 | 28 | 65 | 144 | 0 | 0 | 0 | 0 | 17 | 7 | 6 | 4.51 |
| RP | Peralta, J.Peralta, Joel † >> | 34 | 2010 | R | 95 | 96 | 0 | 8 | 3 | 2.57 | .257 | 1.03 | 6.9 | 2.4 | 8.4 | 133.0 | 102 | 39 | 38 | 11 | 35 | 124 | 0 | 15 | 3 | 0 | 0 | 1 | 0 | 3.02 |
| RP | Marmol, C.Marmol, Carlos >> | 28 | 2010 | R | 70 | 84 | 0 | 5 | 2 | 1.97 | .299 | 1.26 | 5.7 | 5.7 | 11.8 | 109.2 | 69 | 24 | 24 | 1 | 69 | 143 | 0 | 10 | 4 | 0 | 0 | 2 | 8 | 2.45 |
| SP | Cueto, J.Cueto, Johnny >> | 24 | 2010 | R | 38 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Matusz, B.Matusz, Brian >> | 23 | 2010 | L | 27 | 1 | 0 | 0 | 0 | 11.57 | .417 | 2.14 | 13.5 | 9.0 | 4.5 | 2.1 | 3 | 3 | 3 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.50 |
| SP | Greinke, Z.Greinke, Zack >> | 27 | 2010 | R | 48 | 18 | 0 | 3 | 3 | 6.41 | .380 | 1.84 | 14.9 | 2.1 | 5.2 | 26.2 | 43 | 20 | 19 | 3 | 6 | 15 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.04 |