| SP | Hamels, C.Hamels, Cole >> | 27 | 2010 | L | 76 | 4 | 4 | 1 | 2 | 5.01 | .358 | 1.67 | 10.6 | 4.7 | 9.8 | 23.1 | 27 | 13 | 13 | 4 | 12 | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.65 |
| SP | Sabathia, C.Sabathia, CC >> | 30 | 2010 | L | 70 | 4 | 4 | 2 | 0 | 1.93 | .314 | 1.33 | 7.8 | 4.3 | 9.0 | 23.1 | 20 | 6 | 5 | 0 | 11 | 23 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 2.57 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 87 | 7 | 0 | 3 | 0 | 2.70 | .355 | 1.35 | 7.5 | 6.0 | 7.5 | 6.2 | 5 | 2 | 2 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.33 |
| RP | Soria, J.Soria, Joakim >> | 26 | 2010 | R | 69 | 5 | 0 | 0 | 0 | 0.00 | .286 | 1.20 | 7.2 | 3.6 | 7.2 | 5.0 | 4 | 0 | 0 | 0 | 2 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Breslow, C.Breslow, Craig >> | 30 | 2010 | L | 66 | 2 | 0 | 0 | 0 | 0.00 | .333 | 1.50 | - | - | - | 0.2 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Venters, J.Venters, Jonny >> | 25 | 2010 | L | 52 | 3 | 0 | 0 | 0 | 0.00 | .214 | 0.82 | 6.0 | 3.0 | 15.0 | 3.2 | 2 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.67 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 100 | 12 | 0 | 0 | 2 | 6.55 | .411 | 2.09 | 12.3 | 6.5 | 11.5 | 11.0 | 15 | 8 | 8 | 2 | 8 | 14 | 0 | 7 | 1 | 0 | 0 | 0 | 1 | 5.00 |