| SP | Jimenez, U.Jimenez, Ubaldo # | 26 | 2010 | R | 93 | 6 | 6 | 2 | 1 | 5.45 | .331 | 1.49 | 8.8 | 4.8 | 8.0 | 36.1 | 35 | 23 | 22 | 7 | 19 | 32 | 0 | 0 | 0 | 0 | 1 | 0 | 4 | 5.33 |
| SP | Halladay, R.Halladay, Roy $ >> | 33 | 2010 | R | 85 | 6 | 6 | 4 | 1 | 2.11 | .246 | 0.98 | 6.9 | 1.9 | 8.2 | 47.0 | 36 | 11 | 11 | 1 | 10 | 43 | 1 | 0 | 0 | 1 | 5 | 0 | 0 | 2.09 |
| SP | Arroyo, B.Arroyo, Bronson >> | 33 | 2010 | R | 75 | 6 | 6 | 3 | 1 | 2.78 | .327 | 1.46 | 9.3 | 4.1 | 7.5 | 35.2 | 36 | 12 | 11 | 3 | 16 | 29 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 3.83 |
| SP | Wood, T.Wood, Travis $$ >> | 23 | 2010 | L | 87 | 5 | 5 | 3 | 1 | 2.67 | .322 | 1.43 | 10.4 | 2.7 | 7.9 | 33.2 | 38 | 10 | 10 | 2 | 10 | 29 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 2.94 |
| SP | Santana, J.Santana, Johan >> | 31 | 2010 | L | 66 | 5 | 5 | 2 | 1 | 6.03 | .333 | 1.44 | 10.5 | 2.6 | 6.1 | 31.1 | 36 | 21 | 21 | 3 | 9 | 21 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3.97 |
| CL | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 98 | 10 | 0 | 1 | 0 | 2.25 | .250 | 0.92 | 6.0 | 2.3 | 10.5 | 12.0 | 8 | 3 | 3 | 1 | 3 | 14 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 2.75 |
| RP | Fuentes, B.Fuentes, Brian >> | 35 | 2010 | L | 83 | 17 | 0 | 0 | 0 | 2.79 | .256 | 0.93 | 6.0 | 3.0 | 9.0 | 9.2 | 6 | 3 | 3 | 2 | 3 | 9 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.22 |
| RP | Saito, T.Saito, Takashi >> | 40 | 2010 | R | 76 | 13 | 0 | 1 | 0 | 3.27 | .283 | 1.18 | 8.2 | 2.5 | 9.0 | 11.0 | 10 | 4 | 4 | 1 | 3 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Axford, J.Axford, John >> | 27 | 2010 | R | 64 | 5 | 0 | 0 | 1 | 2.16 | .242 | 0.96 | 6.8 | 2.3 | 14.6 | 8.1 | 6 | 2 | 2 | 2 | 2 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| RP | Sanches, B.Sanches, Brian >> | 32 | 2010 | R | 65 | 7 | 0 | 1 | 2 | 4.91 | .185 | 0.68 | 6.4 | 0.0 | 6.4 | 7.1 | 5 | 4 | 4 | 1 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| SP | Dickey, R.Dickey, R.A. >> | 36 | 2010 | R | 58 | 3 | 0 | 1 | 1 | 12.00 | .438 | 2.33 | 13.5 | 7.5 | 4.5 | 6.0 | 9 | 8 | 8 | 1 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.67 |