| SP | Jimenez, U.Jimenez, Ubaldo † $ | 26 | 2010 | R | 93 | 38 | 38 | 18 | 15 | 3.00 | .280 | 1.12 | 6.3 | 3.9 | 7.6 | 257.2 | 179 | 88 | 86 | 18 | 110 | 217 | 2 | 0 | 0 | 1 | 25 | 11 | 10 | 3.63 |
| SP | Wood, T.Wood, Travis $ >> | 23 | 2010 | L | 87 | 36 | 36 | 11 | 13 | 4.34 | .305 | 1.31 | 8.6 | 3.1 | 6.1 | 232.0 | 222 | 112 | 112 | 39 | 81 | 156 | 0 | 0 | 0 | 0 | 19 | 3 | 0 | 4.93 |
| SP | Lilly, T.Lilly, Ted $$ >> | 34 | 2010 | L | 89 | 35 | 35 | 15 | 16 | 5.28 | .307 | 1.30 | 9.2 | 2.5 | 6.5 | 216.2 | 221 | 127 | 127 | 38 | 61 | 157 | 0 | 0 | 0 | 0 | 16 | 6 | 2 | 4.76 |
| SP | Hamels, C.Hamels, Cole # >> | 27 | 2010 | L | 76 | 35 | 35 | 12 | 10 | 4.00 | .285 | 1.18 | 8.1 | 2.5 | 8.7 | 227.0 | 204 | 101 | 101 | 37 | 63 | 219 | 0 | 0 | 0 | 0 | 22 | 5 | 3 | 4.09 |
| SP | Carpenter, C.Carpenter, Chris # >> | 35 | 2010 | R | 67 | 31 | 31 | 11 | 9 | 5.34 | .334 | 1.47 | 10.1 | 3.1 | 6.8 | 195.1 | 219 | 121 | 116 | 29 | 68 | 148 | 0 | 0 | 0 | 0 | 13 | 7 | 5 | 4.57 |
| CL | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 99 | 62 | 0 | 4 | 9 | 3.27 | .312 | 1.33 | 7.9 | 4.1 | 8.6 | 63.1 | 55 | 23 | 23 | 6 | 29 | 60 | 0 | 34 | 4 | 0 | 0 | 2 | 1 | 3.81 |
| RP | O'Day, D.O'Day, Darren # >> | 28 | 2010 | R | 87 | 106 | 0 | 4 | 2 | 4.00 | .289 | 1.21 | 8.8 | 2.1 | 6.5 | 99.0 | 97 | 45 | 44 | 10 | 23 | 71 | 0 | 1 | 5 | 0 | 0 | 1 | 0 | 3.61 |
| RP | Uehara, K.Uehara, Koji >> | 35 | 2010 | R | 81 | 72 | 0 | 6 | 3 | 3.41 | .304 | 1.29 | 9.3 | 2.4 | 10.9 | 63.1 | 65 | 24 | 24 | 7 | 17 | 76 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 2.89 |
| RP | Madson, R.Madson, Ryan >> | 30 | 2010 | R | 75 | 43 | 0 | 3 | 2 | 2.63 | .320 | 1.37 | 8.1 | 4.2 | 7.7 | 41.0 | 37 | 14 | 12 | 4 | 19 | 35 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 4.10 |
| RP | Wilson, B.Wilson, Brian >> | 28 | 2010 | R | 53 | 25 | 0 | 2 | 1 | 1.98 | .243 | 0.96 | 6.5 | 2.3 | 10.5 | 36.1 | 26 | 8 | 8 | 3 | 9 | 42 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.50 |
| SP | Lincecum, T.Lincecum, Tim >> | 26 | 2010 | R | 59 | 15 | 0 | 2 | 1 | 3.25 | .291 | 1.23 | 6.9 | 4.3 | 8.5 | 55.1 | 42 | 20 | 20 | 5 | 26 | 52 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.71 |