| SP | Kershaw, C.Kershaw, Clayton >> | 22 | 2010 | L | 88 | 36 | 36 | 11 | 13 | 3.29 | .281 | 1.15 | 6.9 | 3.4 | 9.1 | 241.0 | 186 | 90 | 88 | 18 | 92 | 245 | 1 | 0 | 0 | 0 | 25 | 5 | 6 | 3.15 |
| SP | Johnson, J.Johnson, Josh >> | 26 | 2010 | R | 90 | 34 | 34 | 12 | 14 | 3.87 | .299 | 1.26 | 8.2 | 3.1 | 9.6 | 211.2 | 193 | 94 | 91 | 18 | 73 | 225 | 0 | 0 | 0 | 0 | 20 | 5 | 14 | 3.09 |
| SP | Halladay, R.Halladay, Roy >> | 33 | 2010 | R | 85 | 33 | 33 | 13 | 12 | 4.51 | .315 | 1.35 | 10.2 | 2.0 | 6.8 | 225.2 | 255 | 119 | 113 | 29 | 50 | 171 | 3 | 0 | 0 | 0 | 17 | 6 | 3 | 3.90 |
| SP | Marcum, S.Marcum, Shaun >> | 29 | 2010 | R | 73 | 31 | 31 | 9 | 11 | 5.37 | .353 | 1.62 | 11.2 | 3.4 | 6.6 | 159.1 | 198 | 98 | 95 | 24 | 60 | 116 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 4.69 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 94 | 95 | 0 | 8 | 6 | 3.51 | .280 | 1.15 | 8.3 | 2.1 | 12.0 | 136.0 | 125 | 53 | 53 | 11 | 31 | 181 | 0 | 9 | 9 | 0 | 0 | 3 | 0 | 2.14 |
| RP | Venters, J.Venters, Jonny >> | 25 | 2010 | L | 52 | 81 | 0 | 9 | 6 | 3.09 | .285 | 1.17 | 7.1 | 3.5 | 8.7 | 90.1 | 71 | 32 | 31 | 5 | 35 | 87 | 0 | 11 | 4 | 0 | 0 | 2 | 7 | 3.02 |
| RP | Hanrahan, J.Hanrahan, Joel >> | 29 | 2010 | R | 41 | 57 | 0 | 4 | 5 | 4.61 | .373 | 1.76 | 10.4 | 5.6 | 9.2 | 56.2 | 65 | 31 | 29 | 9 | 35 | 57 | 0 | 6 | 3 | 0 | 0 | 1 | 2 | 4.98 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 28 | 2010 | R | 23 | 43 | 0 | 2 | 2 | 3.02 | .277 | 1.08 | 6.1 | 3.7 | 6.8 | 41.2 | 28 | 14 | 14 | 2 | 17 | 31 | 0 | 4 | 1 | 0 | 0 | 3 | 6 | 3.59 |
| SP | Westbrook, J.Westbrook, Jake >> | 33 | 2010 | R | 20 | 14 | 0 | 2 | 1 | 6.75 | .360 | 1.69 | 11.3 | 3.9 | 5.6 | 16.0 | 20 | 14 | 12 | 2 | 7 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.69 |