| SP | Johnson, J.Johnson, Josh >> | 26 | 2010 | R | 90 | 21 | 21 | 7 | 6 | 3.99 | .322 | 1.41 | 9.8 | 2.9 | 8.6 | 128.2 | 140 | 61 | 57 | 16 | 41 | 123 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 3.71 |
| SP | Halladay, R.Halladay, Roy $ >> | 33 | 2010 | R | 85 | 21 | 21 | 10 | 5 | 3.82 | .277 | 1.12 | 8.1 | 2.0 | 7.1 | 155.2 | 140 | 67 | 66 | 14 | 35 | 122 | 6 | 0 | 0 | 2 | 11 | 4 | 1 | 3.35 |
| SP | Price, D.Price, David $$ >> | 25 | 2010 | L | 78 | 20 | 20 | 7 | 8 | 4.12 | .314 | 1.36 | 8.0 | 4.3 | 6.4 | 129.0 | 114 | 62 | 59 | 10 | 62 | 92 | 2 | 0 | 0 | 0 | 11 | 1 | 3 | 4.05 |
| SP | Marcum, S.Marcum, Shaun >> | 29 | 2010 | R | 73 | 20 | 20 | 7 | 9 | 4.19 | .308 | 1.30 | 9.5 | 2.1 | 6.4 | 131.0 | 139 | 64 | 61 | 13 | 31 | 93 | 1 | 0 | 0 | 0 | 11 | 5 | 2 | 3.69 |
| SP | Braden, D.Braden, Dallas >> | 27 | 2010 | L | 63 | 20 | 20 | 9 | 6 | 4.61 | .307 | 1.31 | 9.5 | 2.4 | 6.2 | 132.2 | 139 | 69 | 68 | 24 | 35 | 91 | 1 | 0 | 0 | 0 | 11 | 2 | 3 | 4.83 |
| RP | Thornton, M.Thornton, Matt >> | 34 | 2010 | L | 89 | 54 | 0 | 5 | 3 | 4.95 | .367 | 1.74 | 10.5 | 5.2 | 10.7 | 67.1 | 78 | 38 | 37 | 7 | 39 | 80 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 3.72 |
| RP | Marmol, C.Marmol, Carlos >> | 28 | 2010 | R | 70 | 38 | 0 | 1 | 2 | 2.98 | .352 | 1.63 | 8.1 | 6.6 | 11.6 | 42.1 | 38 | 14 | 14 | 3 | 31 | 54 | 0 | 5 | 3 | 0 | 0 | 0 | 1 | 3.57 |
| RP | McClellan, K.McClellan, Kyle >> | 26 | 2010 | R | 59 | 23 | 0 | 3 | 2 | 3.00 | .229 | 0.85 | 6.0 | 1.7 | 9.3 | 27.0 | 18 | 9 | 9 | 6 | 5 | 28 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.48 |
| RP | Hanrahan, J.Hanrahan, Joel >> | 29 | 2010 | R | 41 | 13 | 0 | 2 | 0 | 4.91 | .333 | 1.50 | 10.9 | 3.2 | 11.6 | 14.2 | 17 | 8 | 8 | 3 | 5 | 18 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.29 |
| RP | Fuentes, B.Fuentes, Brian >> | 35 | 2010 | L | 83 | 14 | 0 | 2 | 0 | 2.87 | .230 | 0.89 | 4.2 | 4.2 | 7.2 | 15.2 | 7 | 5 | 5 | 2 | 7 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.53 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 87 | 14 | 0 | 0 | 0 | 0.43 | .203 | 0.76 | 4.7 | 2.1 | 7.3 | 21.0 | 11 | 1 | 1 | 0 | 5 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.10 |