| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 100 | 21 | 21 | 6 | 5 | 4.53 | .329 | 1.46 | 8.7 | 4.4 | 7.1 | 129.0 | 125 | 73 | 65 | 17 | 63 | 102 | 0 | 0 | 0 | 0 | 10 | 2 | 2 | 4.64 |
| SP | Arroyo, B.Arroyo, Bronson >> | 33 | 2010 | R | 75 | 20 | 20 | 5 | 9 | 4.92 | .347 | 1.58 | 11.0 | 3.2 | 5.9 | 111.2 | 136 | 62 | 61 | 16 | 40 | 73 | 0 | 0 | 0 | 0 | 10 | 2 | 1 | 4.69 |
| SP | Kennedy, I.Kennedy, Ian >> | 26 | 2010 | R | 72 | 20 | 20 | 7 | 9 | 4.85 | .349 | 1.58 | 9.5 | 4.8 | 6.6 | 117.0 | 123 | 68 | 63 | 17 | 62 | 86 | 0 | 0 | 0 | 0 | 8 | 3 | 8 | 5.09 |
| SP | Sabathia, C.Sabathia, CC >> | 30 | 2010 | L | 70 | 22 | 20 | 3 | 12 | 4.99 | .317 | 1.39 | 8.8 | 3.6 | 7.0 | 119.0 | 117 | 70 | 66 | 18 | 48 | 93 | 1 | 0 | 0 | 0 | 9 | 1 | 2 | 4.64 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 93 | 62 | 0 | 8 | 4 | 3.10 | .287 | 1.16 | 7.2 | 3.2 | 7.9 | 87.0 | 70 | 34 | 30 | 6 | 31 | 76 | 0 | 1 | 7 | 0 | 0 | 4 | 0 | 3.36 |
| RP | Rhodes, A.Rhodes, Arthur >> | 41 | 2010 | L | 82 | 60 | 0 | 5 | 2 | 2.75 | .280 | 1.13 | 6.9 | 3.3 | 7.7 | 85.0 | 65 | 29 | 26 | 8 | 31 | 73 | 0 | 8 | 2 | 0 | 0 | 3 | 2 | 3.71 |
| RP | Ogando, A.Ogando, Alexi >> | 26 | 2010 | R | 57 | 42 | 0 | 2 | 4 | 4.89 | .339 | 1.46 | 10.1 | 3.2 | 8.1 | 42.1 | 47 | 30 | 23 | 8 | 15 | 38 | 0 | 5 | 1 | 0 | 0 | 3 | 2 | 4.95 |
| RP | Casilla, S.Casilla, Santiago >> | 30 | 2010 | R | 54 | 28 | 0 | 0 | 1 | 5.97 | .353 | 1.64 | 9.3 | 5.8 | 8.0 | 28.2 | 29 | 19 | 19 | 4 | 18 | 25 | 0 | 3 | 0 | 0 | 0 | 0 | 5 | 5.00 |