| SP | deGrom, J.deGrom, Jacob $ >> | 37 | 2025 | R | 97 | 20 | 20 | 6 | 4 | 4.70 | .329 | 1.43 | 10.3 | 2.6 | 9.8 | 111.0 | 127 | 60 | 58 | 10 | 32 | 121 | 0 | 0 | 0 | 0 | 9 | 4 | 3 | 2.96 |
| SP | Cameron, N.Cameron, Noah >> | 25 | 2025 | L | 78 | 19 | 19 | 3 | 9 | 7.21 | .369 | 1.70 | 10.8 | 4.5 | 7.5 | 93.2 | 112 | 82 | 75 | 16 | 47 | 77 | 0 | 0 | 0 | 0 | 5 | 5 | 2 | 5.26 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 64 | 18 | 18 | 6 | 5 | 5.01 | .339 | 1.51 | 10.0 | 3.5 | 10.3 | 97.0 | 108 | 54 | 54 | 11 | 38 | 111 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 3.45 |
| SP | Peralta, F.Peralta, Freddy >> | 29 | 2025 | R | 87 | 19 | 18 | 6 | 5 | 4.58 | .342 | 1.51 | 9.9 | 3.7 | 10.9 | 96.1 | 106 | 49 | 49 | 11 | 39 | 116 | 0 | 0 | 0 | 0 | 4 | 5 | 3 | 3.45 |
| CL | Rodríguez, R.Rodríguez, Randy † $$ >> | 25 | 2025 | R | 95 | 44 | 0 | 3 | 4 | 4.72 | .329 | 1.43 | 9.8 | 3.3 | 10.5 | 47.2 | 51 | 25 | 25 | 3 | 17 | 55 | 0 | 18 | 5 | 0 | 0 | 2 | 3 | 2.70 |
| SU | Jansen, K.Jansen, Kenley >> | 37 | 2025 | R | 89 | 49 | 0 | 4 | 2 | 4.48 | .282 | 1.13 | 7.7 | 2.6 | 8.7 | 60.1 | 51 | 35 | 30 | 8 | 17 | 58 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 3.80 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 88 | 55 | 0 | 4 | 2 | 4.22 | .322 | 1.34 | 8.1 | 4.1 | 10.5 | 59.2 | 53 | 28 | 28 | 2 | 27 | 69 | 0 | 1 | 4 | 0 | 0 | 5 | 0 | 2.73 |
| RP | Whitlock, G.Whitlock, Garrett >> | 29 | 2025 | R | 75 | 53 | 0 | 5 | 2 | 4.42 | .327 | 1.40 | 9.5 | 3.2 | 10.3 | 57.0 | 60 | 28 | 28 | 7 | 20 | 65 | 0 | 1 | 2 | 0 | 0 | 3 | 3 | 3.53 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 64 | 46 | 0 | 1 | 2 | 2.29 | .292 | 1.20 | 8.1 | 2.6 | 12.0 | 51.0 | 46 | 13 | 13 | 3 | 15 | 68 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 2.10 |
| SP | Bello, B.Bello, Brayan >> | 26 | 2025 | R | 55 | 14 | 0 | 2 | 2 | 4.50 | .294 | 1.25 | 8.7 | 2.6 | 7.7 | 28.0 | 27 | 15 | 14 | 5 | 8 | 24 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.46 |