| SP | Pivetta, N.Pivetta, Nick † >> | 32 | 2025 | R | 92 | 26 | 26 | 10 | 8 | 3.36 | .294 | 1.22 | 8.2 | 2.8 | 10.5 | 169.0 | 154 | 64 | 63 | 19 | 53 | 197 | 1 | 0 | 0 | 0 | 17 | 4 | 4 | 3.14 |
| SP | Burrows, M.Burrows, Mike >> | 25 | 2025 | R | 58 | 25 | 25 | 2 | 9 | 6.42 | .368 | 1.68 | 11.2 | 4.0 | 8.9 | 102.1 | 127 | 78 | 73 | 21 | 45 | 101 | 0 | 0 | 0 | 0 | 1 | 7 | 1 | 5.23 |
| SP | Wacha, M.Wacha, Michael # >> | 33 | 2025 | R | 45 | 24 | 24 | 10 | 9 | 5.16 | .312 | 1.34 | 9.1 | 3.0 | 8.6 | 137.2 | 138 | 81 | 79 | 28 | 46 | 131 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 4.82 |
| SP | Giolito, L.Giolito, Lucas # >> | 30 | 2025 | R | 43 | 24 | 24 | 5 | 11 | 6.95 | .372 | 1.76 | 10.0 | 5.9 | 8.1 | 125.2 | 139 | 99 | 97 | 19 | 82 | 112 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 5.20 |
| RP | Pagan, E.Pagan, Emilio >> | 34 | 2025 | R | 95 | 64 | 0 | 4 | 4 | 2.54 | .320 | 1.38 | 7.3 | 5.1 | 10.2 | 92.0 | 75 | 30 | 26 | 6 | 52 | 104 | 0 | 4 | 4 | 0 | 0 | 3 | 0 | 3.38 |
| RP | Santillan, T.Santillan, Tony >> | 28 | 2025 | R | 73 | 66 | 0 | 6 | 4 | 3.63 | .316 | 1.33 | 7.1 | 4.9 | 10.9 | 84.1 | 66 | 34 | 34 | 11 | 46 | 102 | 0 | 5 | 3 | 0 | 0 | 5 | 1 | 4.10 |
| RP | Koenig, J.Koenig, Jared >> | 31 | 2025 | L | 57 | 67 | 0 | 6 | 2 | 3.54 | .308 | 1.30 | 8.1 | 3.5 | 10.6 | 84.0 | 76 | 33 | 33 | 8 | 33 | 99 | 0 | 10 | 4 | 0 | 0 | 3 | 5 | 3.17 |
| RP | Ferguson, T.Ferguson, Tyler >> | 31 | 2025 | R | 45 | 60 | 0 | 5 | 4 | 4.68 | .344 | 1.55 | 9.1 | 4.8 | 8.3 | 65.1 | 66 | 35 | 34 | 8 | 35 | 60 | 0 | 7 | 3 | 0 | 0 | 2 | 3 | 4.46 |
| RP | Scott, T.Scott, Tanner >> | 30 | 2025 | L | 36 | 48 | 0 | 1 | 4 | 3.90 | .267 | 1.08 | 7.6 | 2.2 | 11.4 | 57.2 | 48 | 25 | 25 | 8 | 14 | 72 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 3.09 |
| SP | Berrios, J.Berrios, Jose >> | 31 | 2025 | R | 31 | 30 | 1 | 3 | 5 | 7.08 | .381 | 1.82 | 12.6 | 4.1 | 10.8 | 40.2 | 56 | 33 | 32 | 12 | 18 | 48 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 5.93 |