| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 22 | 22 | 10 | 6 | 3.96 | .303 | 1.27 | 9.2 | 2.3 | 12.3 | 129.2 | 132 | 57 | 57 | 13 | 33 | 177 | 0 | 0 | 0 | 0 | 8 | 4 | 2 | 2.43 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 90 | 21 | 21 | 8 | 3 | 5.04 | .344 | 1.53 | 10.0 | 3.9 | 11.9 | 103.2 | 114 | 60 | 58 | 16 | 45 | 136 | 0 | 0 | 0 | 0 | 3 | 4 | 11 | 3.81 |
| SP | Springs, J.Springs, Jeffrey >> | 32 | 2025 | L | 63 | 20 | 20 | 4 | 4 | 6.08 | .336 | 1.49 | 9.6 | 3.9 | 7.2 | 90.1 | 96 | 65 | 61 | 20 | 39 | 72 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 5.66 |
| CL | Miller, M.Miller, Mason >> | 26 | 2025 | R | 98 | 46 | 0 | 3 | 9 | 5.06 | .322 | 1.35 | 7.3 | 4.9 | 13.2 | 53.1 | 43 | 32 | 30 | 12 | 29 | 78 | 0 | 5 | 4 | 0 | 0 | 4 | 0 | 4.87 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 57 | 0 | 5 | 2 | 2.94 | .257 | 1.01 | 6.7 | 2.4 | 8.6 | 70.1 | 52 | 23 | 23 | 2 | 19 | 67 | 0 | 3 | 2 | 0 | 0 | 2 | 2 | 2.36 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 84 | 57 | 0 | 2 | 2 | 5.10 | .336 | 1.47 | 8.7 | 4.5 | 10.8 | 60.0 | 58 | 35 | 34 | 10 | 30 | 72 | 0 | 5 | 1 | 0 | 0 | 3 | 2 | 4.42 |
| RP | Saalfrank, A.Saalfrank, Andrew >> | 27 | 2025 | L | 83 | 54 | 0 | 5 | 2 | 3.70 | .303 | 1.23 | 8.4 | 2.7 | 6.6 | 56.0 | 52 | 23 | 23 | 7 | 17 | 41 | 0 | 6 | 4 | 0 | 0 | 4 | 2 | 4.29 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 70 | 40 | 0 | 3 | 0 | 4.93 | .327 | 1.46 | 8.1 | 5.2 | 9.0 | 38.1 | 34 | 22 | 21 | 5 | 22 | 38 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 4.45 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 63 | 33 | 0 | 1 | 1 | 6.21 | .307 | 1.27 | 9.0 | 2.7 | 8.5 | 37.2 | 37 | 26 | 26 | 4 | 11 | 35 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.57 |