| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 12 | 12 | 2 | 3 | 3.68 | .322 | 1.34 | 10.3 | 1.8 | 11.2 | 71.0 | 81 | 31 | 29 | 8 | 14 | 88 | 0 | 0 | 0 | 0 | 6 | 6 | 1 | 2.83 |
| SP | Pepiot, R.Pepiot, Ryan >> | 27 | 2025 | R | 77 | 12 | 12 | 4 | 6 | 5.49 | .352 | 1.58 | 9.2 | 5.3 | 9.0 | 60.2 | 61 | 37 | 37 | 8 | 35 | 60 | 0 | 0 | 0 | 0 | 2 | 3 | 2 | 4.63 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 60 | 11 | 11 | 5 | 2 | 4.76 | .339 | 1.52 | 10.7 | 3.0 | 7.1 | 62.1 | 74 | 34 | 33 | 7 | 21 | 49 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 3.95 |
| SU | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 34 | 0 | 1 | 1 | 2.82 | .290 | 1.15 | 7.1 | 3.3 | 9.5 | 38.1 | 30 | 12 | 12 | 3 | 14 | 40 | 0 | 1 | 4 | 0 | 0 | 3 | 2 | 3.26 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 87 | 34 | 0 | 4 | 1 | 2.98 | .314 | 1.37 | 7.9 | 4.5 | 9.0 | 42.1 | 37 | 14 | 14 | 3 | 21 | 42 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 3.43 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 85 | 36 | 0 | 5 | 1 | 3.19 | .267 | 1.06 | 6.5 | 3.3 | 9.0 | 36.2 | 26 | 13 | 13 | 4 | 13 | 36 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 3.61 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 79 | 29 | 0 | 0 | 0 | 4.97 | .360 | 1.66 | 9.6 | 5.3 | 9.9 | 29.0 | 31 | 16 | 16 | 2 | 17 | 32 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 3.55 |
| RP | Estevez, C.Estevez, Carlos >> | 32 | 2025 | R | 71 | 29 | 0 | 2 | 3 | 6.75 | .378 | 1.79 | 11.7 | 4.8 | 7.8 | 30.2 | 39 | 23 | 23 | 4 | 16 | 26 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.70 |