| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 15 | 15 | 4 | 4 | 3.76 | .298 | 1.22 | 8.1 | 2.9 | 10.0 | 91.0 | 82 | 40 | 38 | 12 | 29 | 101 | 0 | 0 | 0 | 0 | 10 | 5 | 1 | 3.62 |
| SP | Gilbert, L.Gilbert, Logan >> | 28 | 2025 | R | 90 | 14 | 14 | 4 | 3 | 4.59 | .338 | 1.44 | 9.0 | 4.1 | 11.0 | 68.2 | 68 | 35 | 35 | 9 | 31 | 83 | 0 | 0 | 0 | 0 | 5 | 6 | 9 | 3.91 |
| SP | Sanchez, C.Sanchez, Cristopher # >> | 28 | 2025 | L | 80 | 14 | 14 | 9 | 2 | 3.40 | .282 | 1.18 | 8.8 | 1.9 | 10.0 | 92.2 | 90 | 38 | 35 | 10 | 19 | 102 | 0 | 0 | 0 | 0 | 10 | 0 | 1 | 2.82 |
| SP | Soriano, J.Soriano, Jose >> | 26 | 2025 | R | 24 | 14 | 14 | 5 | 2 | 3.96 | .332 | 1.45 | 8.9 | 4.3 | 6.0 | 63.2 | 62 | 31 | 28 | 5 | 30 | 42 | 0 | 0 | 0 | 0 | 1 | 3 | 4 | 4.27 |
| RP | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 92 | 36 | 0 | 5 | 3 | 1.60 | .255 | 0.97 | 6.1 | 2.7 | 10.8 | 50.2 | 34 | 11 | 9 | 2 | 15 | 60 | 0 | 1 | 3 | 0 | 0 | 3 | 0 | 2.20 |
| SU | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 30 | 0 | 0 | 1 | 2.27 | .264 | 1.04 | 7.0 | 2.6 | 7.8 | 31.2 | 24 | 8 | 8 | 2 | 9 | 27 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.06 |
| RP | Iglesias, R.Iglesias, Raisel >> | 35 | 2025 | R | 80 | 32 | 0 | 4 | 1 | 2.36 | .285 | 1.17 | 6.4 | 4.2 | 10.6 | 34.1 | 24 | 9 | 9 | 3 | 16 | 40 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 3.29 |
| RP | Thornton, T.Thornton, Trent >> | 31 | 2025 | R | 22 | 27 | 0 | 1 | 2 | 5.45 | .307 | 1.33 | 9.8 | 2.4 | 7.1 | 34.2 | 37 | 23 | 21 | 8 | 9 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.26 |
| SP | Kikuchi, Y.Kikuchi, Yusei >> | 34 | 2025 | L | 17 | 9 | 1 | 2 | 0 | 1.72 | .217 | 0.83 | 4.8 | 3.0 | 10.8 | 15.2 | 8 | 3 | 3 | 2 | 5 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.33 |