| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 16 | 16 | 6 | 3 | 2.65 | .279 | 1.13 | 7.9 | 2.3 | 9.7 | 108.2 | 95 | 32 | 32 | 7 | 28 | 116 | 1 | 0 | 0 | 0 | 11 | 3 | 2 | 2.56 |
| SP | Peralta, F.Peralta, Freddy >> | 29 | 2025 | R | 87 | 15 | 15 | 4 | 3 | 2.52 | .280 | 1.11 | 7.2 | 2.9 | 10.9 | 85.2 | 68 | 24 | 24 | 4 | 27 | 103 | 0 | 0 | 0 | 0 | 8 | 5 | 1 | 2.32 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 67 | 15 | 15 | 4 | 4 | 7.39 | .380 | 1.81 | 13.4 | 2.8 | 9.0 | 67.0 | 100 | 56 | 55 | 18 | 21 | 67 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 5.52 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 35 | 0 | 5 | 0 | 3.46 | .269 | 1.08 | 7.2 | 2.5 | 8.5 | 39.0 | 31 | 15 | 15 | 6 | 11 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Fairbanks, P.Fairbanks, Peter >> | 31 | 2025 | R | 74 | 23 | 0 | 1 | 3 | 3.77 | .256 | 1.03 | 4.9 | 4.4 | 7.3 | 31.0 | 17 | 13 | 13 | 5 | 15 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.94 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 79 | 32 | 0 | 2 | 2 | 2.66 | .279 | 1.16 | 7.8 | 2.7 | 8.4 | 44.0 | 38 | 13 | 13 | 3 | 13 | 41 | 0 | 1 | 4 | 0 | 0 | 0 | 2 | 2.91 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 28 | 0 | 2 | 1 | 3.46 | .304 | 1.27 | 5.2 | 6.2 | 12.5 | 26.0 | 15 | 10 | 10 | 3 | 18 | 36 | 0 | 18 | 2 | 0 | 0 | 1 | 0 | 3.92 |