| SP | Brown, H.Brown, Hunter >> | 26 | 2025 | R | 92 | 16 | 16 | 5 | 6 | 2.99 | .284 | 1.17 | 6.9 | 3.7 | 12.4 | 102.1 | 78 | 34 | 34 | 10 | 42 | 140 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 2.82 |
| SP | Springs, J.Springs, Jeffrey >> | 32 | 2025 | L | 63 | 16 | 16 | 4 | 7 | 5.61 | .333 | 1.50 | 9.7 | 3.9 | 8.6 | 86.2 | 93 | 56 | 54 | 16 | 37 | 82 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.80 |
| SP | Bello, B.Bello, Brayan # >> | 26 | 2025 | R | 55 | 16 | 16 | 3 | 7 | 5.18 | .327 | 1.43 | 9.4 | 3.5 | 7.9 | 92.0 | 96 | 54 | 53 | 12 | 36 | 81 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 4.17 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 45 | 16 | 16 | 3 | 6 | 6.43 | .359 | 1.65 | 10.9 | 4.0 | 5.9 | 84.0 | 102 | 62 | 60 | 19 | 37 | 55 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 6.02 |
| SP | Scherzer, M.Scherzer, Max >> | 41 | 2025 | R | 32 | 16 | 16 | 5 | 5 | 5.31 | .352 | 1.55 | 10.8 | 3.1 | 7.8 | 83.0 | 100 | 49 | 49 | 8 | 29 | 72 | 0 | 0 | 0 | 0 | 5 | 6 | 2 | 3.78 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 71 | 43 | 0 | 1 | 1 | 5.13 | .324 | 1.44 | 10.3 | 2.7 | 8.5 | 54.1 | 62 | 31 | 31 | 11 | 16 | 51 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.65 |
| RP | Phillips, T.Phillips, Tyler >> | 27 | 2025 | R | 55 | 43 | 0 | 2 | 1 | 4.01 | .316 | 1.34 | 8.9 | 3.3 | 8.7 | 60.2 | 59 | 29 | 27 | 7 | 22 | 58 | 0 | 3 | 2 | 0 | 0 | 3 | 3 | 3.83 |
| RP | Detmers, R.Detmers, Reid >> | 25 | 2025 | L | 35 | 27 | 0 | 3 | 1 | 4.40 | .344 | 1.57 | 8.4 | 6.1 | 13.5 | 28.2 | 26 | 14 | 14 | 0 | 19 | 42 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.04 |