| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 29 | 29 | 6 | 13 | 3.60 | .302 | 1.27 | 8.5 | 2.9 | 9.3 | 175.0 | 165 | 71 | 70 | 16 | 57 | 180 | 1 | 0 | 0 | 0 | 17 | 5 | 3 | 3.19 |
| SP | Pepiot, R.Pepiot, Ryan # >> | 27 | 2025 | R | 77 | 29 | 29 | 8 | 14 | 4.77 | .310 | 1.32 | 8.5 | 3.4 | 10.2 | 160.1 | 151 | 86 | 85 | 17 | 61 | 182 | 0 | 0 | 0 | 0 | 10 | 4 | 6 | 3.33 |
| SP | Burrows, M.Burrows, Mike >> | 25 | 2025 | R | 58 | 28 | 28 | 1 | 12 | 5.64 | .341 | 1.53 | 10.2 | 3.6 | 10.9 | 121.1 | 137 | 79 | 76 | 26 | 49 | 146 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 4.64 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 45 | 28 | 28 | 7 | 15 | 6.72 | .363 | 1.68 | 11.6 | 3.6 | 6.9 | 143.1 | 184 | 107 | 107 | 35 | 57 | 109 | 1 | 0 | 0 | 1 | 8 | 4 | 2 | 5.94 |
| SP | Quintana, J.Quintana, Jose >> | 36 | 2025 | L | 34 | 30 | 27 | 6 | 15 | 5.56 | .348 | 1.56 | 10.0 | 4.1 | 8.2 | 147.1 | 163 | 98 | 91 | 28 | 67 | 134 | 0 | 1 | 0 | 0 | 7 | 6 | 4 | 5.14 |
| RP | Okert, S.Okert, Steven † >> | 33 | 2025 | L | 97 | 92 | 0 | 9 | 4 | 3.69 | .312 | 1.33 | 9.1 | 2.9 | 10.6 | 127.0 | 128 | 52 | 52 | 11 | 41 | 150 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 2.83 |
| RP | Saalfrank, A.Saalfrank, Andrew >> | 27 | 2025 | L | 83 | 89 | 0 | 5 | 7 | 4.43 | .301 | 1.24 | 6.9 | 4.3 | 7.0 | 111.2 | 85 | 56 | 55 | 8 | 53 | 86 | 0 | 8 | 5 | 0 | 0 | 6 | 6 | 3.98 |
| RP | Phillips, T.Phillips, Tyler >> | 27 | 2025 | R | 55 | 78 | 0 | 1 | 5 | 3.42 | .309 | 1.32 | 9.3 | 2.7 | 7.4 | 102.2 | 105 | 40 | 39 | 13 | 31 | 84 | 0 | 5 | 2 | 0 | 0 | 2 | 4 | 3.98 |