| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 16 | 16 | 6 | 8 | 3.92 | .302 | 1.23 | 9.1 | 2.1 | 10.8 | 105.2 | 106 | 46 | 46 | 11 | 24 | 126 | 1 | 0 | 0 | 0 | 10 | 7 | 3 | 2.85 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 80 | 16 | 16 | 2 | 5 | 5.28 | .347 | 1.56 | 10.2 | 4.0 | 9.7 | 93.2 | 105 | 59 | 55 | 11 | 41 | 100 | 0 | 0 | 0 | 0 | 8 | 3 | 6 | 3.81 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 59 | 15 | 15 | 3 | 9 | 6.00 | .348 | 1.57 | 10.7 | 3.4 | 8.4 | 90.0 | 107 | 74 | 60 | 21 | 34 | 84 | 0 | 0 | 0 | 0 | 5 | 3 | 3 | 5.40 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 42 | 0 | 2 | 3 | 4.78 | .289 | 1.18 | 7.0 | 3.7 | 12.7 | 58.1 | 45 | 32 | 31 | 5 | 24 | 82 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 2.64 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 43 | 0 | 5 | 5 | 4.70 | .340 | 1.47 | 6.9 | 6.5 | 10.2 | 51.2 | 39 | 30 | 27 | 3 | 37 | 58 | 0 | 3 | 4 | 0 | 0 | 4 | 7 | 3.90 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 88 | 38 | 0 | 1 | 2 | 3.30 | .328 | 1.42 | 9.2 | 3.8 | 10.5 | 43.2 | 44 | 18 | 16 | 4 | 18 | 50 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.28 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 87 | 26 | 0 | 4 | 1 | 2.61 | .290 | 1.19 | 8.4 | 2.3 | 10.2 | 31.0 | 29 | 10 | 9 | 4 | 8 | 35 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.29 |
| RP | Iglesias, R.Iglesias, Raisel >> | 35 | 2025 | R | 80 | 11 | 0 | 1 | 2 | 2.84 | .333 | 1.50 | 9.8 | 4.5 | 8.3 | 12.2 | 13 | 6 | 4 | 1 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |