| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 23 | 23 | 9 | 11 | 3.88 | .298 | 1.25 | 8.5 | 2.8 | 8.9 | 143.2 | 135 | 62 | 62 | 11 | 44 | 141 | 0 | 0 | 0 | 0 | 16 | 4 | 0 | 3.03 |
| SP | Williams, G.Williams, Gavin >> | 25 | 2025 | R | 65 | 22 | 22 | 7 | 8 | 5.43 | .353 | 1.61 | 9.4 | 5.1 | 9.5 | 116.0 | 121 | 70 | 70 | 15 | 66 | 123 | 0 | 0 | 0 | 0 | 8 | 3 | 8 | 4.34 |
| SP | Bibee, T.Bibee, Tanner >> | 26 | 2025 | R | 54 | 22 | 22 | 5 | 10 | 5.68 | .355 | 1.63 | 10.2 | 4.4 | 7.2 | 130.0 | 148 | 87 | 82 | 15 | 64 | 104 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 4.45 |
| RP | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 98 | 57 | 0 | 2 | 5 | 3.69 | .276 | 1.11 | 6.9 | 3.1 | 9.7 | 105.0 | 81 | 43 | 43 | 13 | 36 | 113 | 0 | 3 | 6 | 0 | 0 | 3 | 0 | 3.57 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 77 | 54 | 0 | 1 | 2 | 2.50 | .288 | 1.16 | 7.2 | 3.4 | 8.5 | 75.2 | 60 | 21 | 21 | 5 | 28 | 71 | 0 | 4 | 2 | 0 | 0 | 4 | 1 | 3.25 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 60 | 54 | 0 | 2 | 1 | 4.85 | .328 | 1.42 | 8.5 | 4.3 | 11.1 | 52.0 | 49 | 28 | 28 | 4 | 25 | 64 | 0 | 7 | 2 | 0 | 0 | 2 | 1 | 3.10 |
| RP | Gaddis, H.Gaddis, Hunter >> | 27 | 2025 | R | 52 | 33 | 0 | 3 | 2 | 3.79 | .359 | 1.65 | 10.0 | 5.1 | 10.3 | 35.2 | 39 | 15 | 15 | 1 | 20 | 40 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 2.89 |
| RP | Varland, L.Varland, Louie >> | 27 | 2025 | R | 44 | 36 | 0 | 4 | 3 | 3.86 | .335 | 1.51 | 10.0 | 3.6 | 11.1 | 35.0 | 39 | 17 | 15 | 3 | 14 | 43 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.86 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 45 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Keller, M.Keller, Mitch >> | 29 | 2025 | R | 40 | 12 | 0 | 3 | 1 | 2.35 | .220 | 0.85 | 6.0 | 1.8 | 7.8 | 15.1 | 10 | 4 | 4 | 1 | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.73 |