| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 100 | 28 | 28 | 9 | 10 | 3.51 | .276 | 1.12 | 8.3 | 1.8 | 10.8 | 189.2 | 175 | 77 | 74 | 18 | 37 | 227 | 1 | 0 | 0 | 0 | 18 | 5 | 4 | 2.50 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 86 | 27 | 27 | 3 | 10 | 5.41 | .345 | 1.54 | 8.5 | 5.3 | 11.1 | 133.0 | 126 | 80 | 80 | 21 | 79 | 164 | 0 | 0 | 0 | 0 | 4 | 5 | 6 | 4.48 |
| SP | Lodolo, N.Lodolo, Nick >> | 27 | 2025 | L | 75 | 28 | 27 | 14 | 7 | 5.20 | .323 | 1.40 | 10.2 | 2.4 | 9.0 | 152.1 | 172 | 89 | 88 | 23 | 41 | 152 | 0 | 0 | 0 | 0 | 10 | 5 | 0 | 3.88 |
| RP | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 92 | 70 | 0 | 8 | 3 | 3.45 | .284 | 1.18 | 8.8 | 1.8 | 9.6 | 94.0 | 92 | 37 | 36 | 13 | 19 | 100 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 3.31 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 87 | 64 | 0 | 5 | 3 | 2.97 | .286 | 1.19 | 7.4 | 3.4 | 11.2 | 75.2 | 62 | 25 | 25 | 13 | 28 | 93 | 0 | 3 | 4 | 0 | 0 | 1 | 0 | 3.93 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 82 | 62 | 0 | 7 | 1 | 3.05 | .285 | 1.15 | 7.2 | 3.3 | 8.9 | 73.2 | 58 | 26 | 25 | 8 | 27 | 72 | 0 | 1 | 1 | 0 | 0 | 3 | 2 | 3.68 |
| RP | Mattson, I.Mattson, Isaac >> | 29 | 2025 | R | 68 | 43 | 0 | 3 | 2 | 4.62 | .327 | 1.46 | 9.0 | 4.3 | 6.8 | 48.2 | 48 | 26 | 25 | 6 | 23 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.56 |
| SP | Kikuchi, Y.Kikuchi, Yusei >> | 34 | 2025 | L | 17 | 5 | 0 | 0 | 1 | 15.43 | .462 | 2.57 | 13.5 | 13.5 | 11.3 | 4.2 | 6 | 8 | 8 | 2 | 6 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 11.50 |