| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 25 | 25 | 12 | 6 | 4.72 | .316 | 1.36 | 10.0 | 2.2 | 10.2 | 139.1 | 155 | 79 | 73 | 15 | 34 | 157 | 0 | 0 | 0 | 0 | 14 | 4 | 2 | 2.96 |
| SP | Peralta, F.Peralta, Freddy # >> | 29 | 2025 | R | 87 | 22 | 22 | 10 | 8 | 4.25 | .334 | 1.50 | 9.7 | 3.8 | 10.2 | 114.1 | 123 | 56 | 54 | 17 | 48 | 129 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 3.96 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 82 | 24 | 24 | 10 | 6 | 3.46 | .292 | 1.23 | 8.3 | 2.8 | 8.3 | 143.0 | 132 | 60 | 55 | 18 | 44 | 132 | 0 | 0 | 0 | 0 | 12 | 1 | 5 | 3.73 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 80 | 23 | 23 | 11 | 6 | 4.09 | .291 | 1.21 | 8.7 | 2.3 | 9.8 | 140.2 | 135 | 64 | 64 | 21 | 35 | 152 | 3 | 0 | 0 | 0 | 13 | 3 | 5 | 3.59 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 64 | 23 | 23 | 8 | 6 | 5.07 | .327 | 1.41 | 9.4 | 3.4 | 10.7 | 115.1 | 120 | 65 | 65 | 18 | 43 | 137 | 0 | 0 | 0 | 0 | 10 | 5 | 1 | 3.90 |
| RP | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 98 | 62 | 0 | 8 | 1 | 3.81 | .292 | 1.21 | 6.7 | 4.2 | 11.0 | 99.1 | 74 | 44 | 42 | 4 | 46 | 121 | 0 | 10 | 2 | 0 | 0 | 3 | 4 | 2.57 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 84 | 51 | 0 | 3 | 4 | 4.73 | .336 | 1.48 | 9.6 | 3.9 | 10.1 | 64.2 | 68 | 37 | 34 | 7 | 28 | 72 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 3.58 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 73 | 45 | 0 | 2 | 2 | 2.21 | .260 | 1.06 | 6.5 | 3.1 | 11.0 | 53.0 | 38 | 16 | 13 | 4 | 18 | 65 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 2.55 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 69 | 39 | 0 | 3 | 2 | 5.27 | .332 | 1.44 | 10.1 | 2.9 | 7.2 | 41.0 | 46 | 24 | 24 | 7 | 13 | 33 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.71 |
| RP | Slaten, J.Slaten, Justin >> | 27 | 2025 | R | 62 | 36 | 0 | 1 | 1 | 3.76 | .326 | 1.45 | 8.8 | 4.5 | 7.9 | 40.2 | 39 | 18 | 17 | 3 | 20 | 35 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 3.73 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 59 | 18 | 2 | 3 | 3 | 5.88 | .398 | 1.96 | 12.3 | 5.5 | 8.3 | 41.1 | 56 | 27 | 27 | 4 | 25 | 38 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 4.32 |