| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 100 | 8 | 8 | 3 | 5 | 4.81 | .308 | 1.27 | 9.0 | 2.6 | 11.8 | 48.2 | 48 | 26 | 26 | 9 | 14 | 63 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 3.88 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 86 | 7 | 7 | 4 | 2 | 4.46 | .313 | 1.34 | 7.7 | 4.5 | 10.6 | 34.1 | 29 | 17 | 17 | 3 | 17 | 40 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 3.38 |
| SP | Pepiot, R.Pepiot, Ryan >> | 27 | 2025 | R | 77 | 7 | 7 | 2 | 0 | 3.98 | .321 | 1.40 | 9.2 | 3.3 | 10.3 | 43.0 | 44 | 19 | 19 | 1 | 16 | 49 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 2.21 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 67 | 7 | 7 | 3 | 3 | 3.50 | .321 | 1.37 | 8.8 | 3.8 | 8.6 | 43.2 | 42 | 17 | 17 | 4 | 18 | 41 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 3.70 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 12 | 0 | 1 | 0 | 0.00 | .200 | 0.75 | 2.8 | 4.2 | 15.2 | 13.1 | 4 | 0 | 0 | 0 | 6 | 22 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Bazardo, E.Bazardo, Eduard >> | 29 | 2025 | R | 87 | 21 | 0 | 0 | 0 | 1.04 | .291 | 1.23 | 6.2 | 4.8 | 10.4 | 26.0 | 18 | 3 | 3 | 0 | 14 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.31 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 77 | 15 | 0 | 1 | 0 | 0.00 | .219 | 0.84 | 3.9 | 3.9 | 8.4 | 16.2 | 7 | 0 | 0 | 0 | 7 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.44 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 63 | 8 | 0 | 1 | 0 | 1.74 | .279 | 1.16 | 8.1 | 2.7 | 5.4 | 10.1 | 9 | 2 | 2 | 0 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.70 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 60 | 2 | 0 | 1 | 0 | 1.69 | .273 | 0.94 | 9.0 | 0.0 | 5.4 | 5.1 | 5 | 1 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.00 |