| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 6 | 6 | 2 | 2 | 4.93 | .354 | 1.62 | 11.4 | 3.4 | 8.7 | 34.2 | 43 | 19 | 19 | 2 | 13 | 33 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3.06 |
| SP | Singer, B.Singer, Brady >> | 28 | 2025 | R | 59 | 6 | 6 | 3 | 2 | 4.81 | .322 | 1.37 | 9.0 | 3.5 | 8.7 | 33.2 | 33 | 18 | 18 | 6 | 13 | 32 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.79 |
| SP | Kershaw, C.Kershaw, Clayton # >> | 37 | 2025 | L | 57 | 7 | 6 | 2 | 2 | 5.23 | .367 | 1.68 | 11.9 | 3.2 | 8.7 | 31.0 | 41 | 22 | 18 | 3 | 11 | 30 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3.58 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 45 | 6 | 6 | 3 | 1 | 5.29 | .370 | 1.70 | 11.0 | 4.5 | 5.1 | 32.1 | 39 | 19 | 19 | 5 | 16 | 18 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 5.59 |
| RP | Rodríguez, R.Rodríguez, Randy >> | 25 | 2025 | R | 95 | 16 | 0 | 2 | 1 | 4.56 | .290 | 1.23 | 8.2 | 3.1 | 12.5 | 23.2 | 21 | 12 | 12 | 1 | 8 | 32 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 1.83 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 82 | 17 | 0 | 1 | 1 | 6.00 | .344 | 1.57 | 7.7 | 6.4 | 13.7 | 21.0 | 18 | 15 | 14 | 3 | 15 | 32 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.95 |
| RP | Mattson, I.Mattson, Isaac >> | 29 | 2025 | R | 68 | 15 | 0 | 2 | 1 | 3.20 | .314 | 1.37 | 8.5 | 4.3 | 10.4 | 19.2 | 18 | 8 | 7 | 2 | 9 | 22 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Schreiber, J.Schreiber, John >> | 31 | 2025 | R | 47 | 12 | 0 | 0 | 2 | 6.35 | .424 | 2.21 | 12.3 | 8.2 | 9.8 | 11.1 | 15 | 8 | 8 | 2 | 10 | 12 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.91 |
| SP | Patrick, C.Patrick, Chad >> | 26 | 2025 | R | 44 | 10 | 0 | 0 | 0 | 5.40 | .394 | 1.95 | 11.7 | 5.9 | 12.2 | 20.0 | 26 | 12 | 12 | 6 | 13 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.15 |