| SP | Skubal, T.Skubal, Tarik $$ >> | 28 | 2025 | L | 100 | 6 | 6 | 4 | 2 | 2.68 | .239 | 0.94 | 5.9 | 2.7 | 11.0 | 40.1 | 26 | 12 | 12 | 4 | 12 | 49 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 2.75 |
| SP | Schwellenbach, S.Schwellenbach, Spencer $ >> | 25 | 2025 | R | 85 | 6 | 6 | 3 | 1 | 2.53 | .273 | 1.13 | 7.7 | 2.6 | 7.7 | 42.2 | 36 | 12 | 12 | 7 | 12 | 36 | 0 | 0 | 0 | 0 | 5 | 0 | 1 | 4.31 |
| CL | Chapman, A.Chapman, Aroldis $ >> | 37 | 2025 | L | 100 | 7 | 0 | 0 | 2 | 6.75 | .200 | 0.75 | 5.4 | 1.8 | 10.8 | 5.1 | 3 | 4 | 4 | 2 | 1 | 6 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 6.40 |
| RP | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 92 | 14 | 0 | 0 | 2 | 4.11 | .270 | 1.11 | 6.0 | 4.2 | 6.6 | 15.1 | 10 | 8 | 7 | 3 | 7 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.53 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 79 | 14 | 0 | 0 | 1 | 3.65 | .315 | 1.30 | 9.0 | 3.0 | 12.0 | 12.1 | 12 | 7 | 5 | 3 | 4 | 16 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 4.83 |
| RP | Whitlock, G.Whitlock, Garrett >> | 29 | 2025 | R | 75 | 11 | 0 | 1 | 0 | 2.53 | .333 | 1.50 | 10.8 | 3.6 | 4.5 | 10.2 | 12 | 3 | 3 | 0 | 4 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Coulombe, D.Coulombe, Daniel >> | 35 | 2025 | L | 65 | 19 | 0 | 0 | 1 | 4.70 | .343 | 1.50 | 9.0 | 4.8 | 10.2 | 15.1 | 15 | 10 | 8 | 3 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.13 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 59 | 3 | 0 | 0 | 1 | 5.40 | .375 | 1.80 | 11.7 | 4.5 | 7.2 | 10.0 | 13 | 6 | 6 | 2 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.50 |