| SP | Skubal, T.Skubal, Tarik $ >> | 28 | 2025 | L | 100 | 10 | 10 | 6 | 1 | 2.85 | .253 | 1.00 | 7.4 | 1.8 | 9.6 | 72.2 | 59 | 23 | 23 | 3 | 14 | 77 | 1 | 0 | 0 | 1 | 7 | 1 | 0 | 2.03 |
| SP | Perez, E.Perez, Eury $ >> | 22 | 2025 | R | 89 | 10 | 10 | 4 | 1 | 3.23 | .264 | 1.08 | 7.1 | 2.5 | 10.7 | 53.0 | 42 | 19 | 19 | 5 | 15 | 63 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 2.70 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 57 | 9 | 9 | 4 | 2 | 4.89 | .335 | 1.46 | 8.6 | 4.7 | 9.4 | 42.1 | 40 | 23 | 23 | 2 | 22 | 44 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 3.24 |
| CL | Okert, S.Okert, Steven >> | 33 | 2025 | L | 97 | 20 | 0 | 1 | 2 | 2.19 | .221 | 0.85 | 5.6 | 2.3 | 8.3 | 24.2 | 15 | 6 | 6 | 1 | 6 | 22 | 0 | 10 | 1 | 0 | 0 | 0 | 0 | 2.46 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 30 | 0 | 2 | 3 | 4.04 | .296 | 1.23 | 7.5 | 3.9 | 6.7 | 35.2 | 29 | 16 | 16 | 3 | 15 | 26 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 84 | 24 | 0 | 1 | 3 | 4.73 | .287 | 1.21 | 7.3 | 3.7 | 11.3 | 32.1 | 26 | 17 | 17 | 3 | 13 | 40 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 2.94 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 64 | 26 | 0 | 1 | 0 | 1.61 | .229 | 0.89 | 5.5 | 2.6 | 8.0 | 28.0 | 17 | 5 | 5 | 1 | 8 | 25 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.54 |
| RP | Whitlock, G.Whitlock, Garrett >> | 29 | 2025 | R | 75 | 20 | 0 | 1 | 0 | 5.06 | .319 | 1.36 | 8.6 | 3.9 | 10.3 | 21.1 | 20 | 12 | 12 | 3 | 9 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.00 |