| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 33 | 33 | 14 | 13 | 3.53 | .299 | 1.26 | 8.0 | 3.4 | 10.7 | 201.1 | 178 | 92 | 79 | 24 | 76 | 239 | 0 | 0 | 0 | 0 | 18 | 4 | 4 | 3.37 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 79 | 32 | 32 | 8 | 13 | 4.30 | .333 | 1.47 | 9.5 | 3.8 | 6.7 | 171.2 | 180 | 82 | 82 | 21 | 72 | 127 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 4.46 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 73 | 32 | 32 | 8 | 13 | 5.09 | .346 | 1.56 | 10.4 | 3.7 | 8.5 | 178.2 | 205 | 105 | 101 | 32 | 73 | 169 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 4.75 |
| SP | Castillo, L.Castillo, Luis # >> | 32 | 2025 | R | 67 | 32 | 31 | 18 | 9 | 4.37 | .301 | 1.27 | 8.7 | 2.8 | 8.3 | 185.1 | 179 | 100 | 90 | 26 | 57 | 170 | 1 | 0 | 0 | 0 | 17 | 3 | 3 | 3.96 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 91 | 88 | 0 | 7 | 9 | 3.44 | .293 | 1.22 | 5.9 | 5.2 | 11.9 | 104.2 | 68 | 40 | 40 | 10 | 60 | 137 | 0 | 4 | 2 | 0 | 0 | 2 | 10 | 3.40 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 81 | 72 | 0 | 3 | 3 | 5.22 | .324 | 1.40 | 8.5 | 4.1 | 10.3 | 79.1 | 75 | 48 | 46 | 10 | 36 | 90 | 0 | 3 | 4 | 0 | 0 | 3 | 5 | 3.85 |
| RP | Strahm, M.Strahm, Matt >> | 33 | 2025 | L | 73 | 109 | 0 | 5 | 1 | 3.64 | .290 | 1.19 | 7.8 | 3.0 | 8.4 | 96.1 | 83 | 40 | 39 | 14 | 32 | 90 | 0 | 2 | 5 | 0 | 0 | 3 | 5 | 4.11 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 70 | 62 | 0 | 3 | 1 | 2.65 | .296 | 1.23 | 7.3 | 3.9 | 10.8 | 74.2 | 60 | 23 | 22 | 8 | 32 | 89 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 3.38 |