| SP | Skubal, T.Skubal, Tarik † >> | 28 | 2025 | L | 100 | 33 | 33 | 15 | 9 | 2.89 | .255 | 1.00 | 7.0 | 2.1 | 10.6 | 233.1 | 180 | 77 | 75 | 35 | 54 | 274 | 1 | 0 | 0 | 0 | 21 | 6 | 5 | 3.37 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 89 | 32 | 32 | 12 | 14 | 4.15 | .309 | 1.31 | 8.7 | 3.1 | 10.6 | 214.2 | 208 | 106 | 99 | 27 | 73 | 253 | 2 | 0 | 0 | 0 | 17 | 7 | 6 | 3.40 |
| SP | Cameron, N.Cameron, Noah >> | 25 | 2025 | L | 81 | 32 | 32 | 14 | 11 | 4.11 | .312 | 1.34 | 8.6 | 3.6 | 7.9 | 190.2 | 181 | 95 | 87 | 29 | 75 | 166 | 0 | 0 | 0 | 0 | 14 | 3 | 5 | 4.47 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 71 | 32 | 32 | 13 | 9 | 4.22 | .309 | 1.28 | 8.4 | 3.2 | 8.4 | 194.0 | 181 | 93 | 91 | 22 | 68 | 180 | 0 | 0 | 0 | 0 | 15 | 11 | 2 | 3.84 |
| SP | Kirby, G.Kirby, George >> | 27 | 2025 | R | 66 | 31 | 31 | 7 | 12 | 4.93 | .318 | 1.37 | 9.6 | 2.7 | 10.4 | 177.0 | 189 | 99 | 97 | 24 | 54 | 205 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 3.45 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 89 | 0 | 2 | 4 | 2.57 | .242 | 0.94 | 6.1 | 2.4 | 11.0 | 126.0 | 85 | 37 | 36 | 10 | 33 | 154 | 0 | 10 | 6 | 0 | 0 | 3 | 11 | 2.44 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 89 | 81 | 0 | 7 | 5 | 3.59 | .302 | 1.26 | 6.6 | 4.8 | 10.9 | 100.1 | 73 | 41 | 40 | 10 | 53 | 121 | 0 | 9 | 3 | 0 | 0 | 4 | 0 | 3.59 |
| RP | Weaver, L.Weaver, Luke >> | 31 | 2025 | R | 83 | 69 | 0 | 4 | 2 | 4.52 | .276 | 1.15 | 7.5 | 2.9 | 10.5 | 77.2 | 64 | 42 | 39 | 15 | 25 | 90 | 0 | 11 | 3 | 0 | 0 | 0 | 1 | 4.17 |
| RP | Saalfrank, A.Saalfrank, Andrew >> | 27 | 2025 | L | 82 | 53 | 0 | 6 | 4 | 3.19 | .297 | 1.19 | 8.5 | 2.4 | 6.3 | 53.2 | 50 | 20 | 19 | 3 | 14 | 37 | 0 | 6 | 1 | 0 | 0 | 4 | 3 | 3.36 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 78 | 32 | 0 | 5 | 2 | 1.83 | .275 | 1.11 | 7.4 | 2.6 | 9.0 | 34.1 | 28 | 7 | 7 | 2 | 10 | 34 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 2.74 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 68 | 32 | 0 | 1 | 2 | 3.44 | .290 | 1.23 | 9.0 | 2.3 | 8.5 | 36.2 | 36 | 16 | 14 | 6 | 9 | 34 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.03 |