| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 12 | 12 | 3 | 6 | 3.81 | .314 | 1.36 | 9.6 | 2.8 | 8.9 | 75.2 | 80 | 34 | 32 | 8 | 23 | 74 | 1 | 0 | 0 | 0 | 8 | 1 | 1 | 3.37 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 79 | 12 | 12 | 2 | 5 | 6.41 | .365 | 1.69 | 12.1 | 3.2 | 8.0 | 53.1 | 71 | 38 | 38 | 12 | 19 | 47 | 0 | 0 | 0 | 0 | 3 | 2 | 1 | 5.36 |
| SP | Williams, G.Williams, Gavin >> | 25 | 2025 | R | 69 | 11 | 11 | 0 | 2 | 6.09 | .369 | 1.76 | 10.3 | 5.7 | 9.5 | 54.2 | 62 | 37 | 37 | 13 | 34 | 57 | 0 | 0 | 0 | 0 | 1 | 0 | 6 | 5.91 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 60 | 12 | 11 | 1 | 7 | 8.87 | .355 | 1.63 | 11.3 | 3.5 | 6.8 | 46.2 | 58 | 47 | 46 | 16 | 18 | 35 | 0 | 1 | 0 | 0 | 1 | 1 | 3 | 7.24 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 81 | 35 | 0 | 3 | 0 | 7.46 | .371 | 1.69 | 11.3 | 3.9 | 10.5 | 35.0 | 44 | 31 | 29 | 10 | 15 | 41 | 0 | 0 | 2 | 0 | 0 | 3 | 4 | 5.91 |
| SP | Taillon, J.Taillon, Jameson >> | 33 | 2025 | R | 77 | 23 | 0 | 3 | 3 | 5.65 | .353 | 1.61 | 13.0 | 1.8 | 8.0 | 36.2 | 52 | 24 | 23 | 8 | 7 | 32 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.78 |