| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 34 | 34 | 7 | 8 | 0.42 | .118 | 0.39 | 2.7 | 0.8 | 9.3 | 300.1 | 90 | 14 | 14 | 4 | 28 | 311 | 9 | 0 | 0 | 4 | 34 | 2 | 4 | 1.40 |
| SP | Kluber, C.Kluber, Corey † >> | 31 | 2017 | R | 96 | 34 | 34 | 16 | 8 | 0.32 | .123 | 0.41 | 2.8 | 0.9 | 8.6 | 310.2 | 98 | 13 | 11 | 0 | 30 | 295 | 20 | 0 | 0 | 11 | 34 | 3 | 4 | 1.42 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 98 | 74 | 0 | 3 | 3 | 0.22 | .108 | 0.35 | 2.5 | 0.7 | 8.7 | 83.0 | 23 | 3 | 2 | 0 | 6 | 80 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 1.33 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 90 | 54 | 0 | 2 | 2 | 0.11 | .138 | 0.48 | 2.8 | 1.6 | 9.3 | 81.0 | 25 | 2 | 1 | 0 | 14 | 84 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 1.44 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 97 | 67 | 0 | 1 | 0 | 0.00 | .058 | 0.18 | 1.5 | 0.2 | 9.6 | 43.2 | 7 | 0 | 0 | 0 | 1 | 46 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0.93 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 88 | 32 | 0 | 1 | 6 | 1.04 | .212 | 0.81 | 5.3 | 2.1 | 11.0 | 60.2 | 35 | 8 | 7 | 1 | 14 | 73 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.48 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 82 | 47 | 0 | 6 | 1 | 0.20 | .095 | 0.32 | 1.9 | 1.0 | 9.2 | 92.0 | 19 | 2 | 2 | 1 | 10 | 94 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1.42 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 80 | 41 | 0 | 6 | 5 | 0.53 | .130 | 0.45 | 3.1 | 1.0 | 5.2 | 118.1 | 40 | 7 | 7 | 2 | 13 | 68 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 2.40 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 74 | 34 | 0 | 0 | 1 | 0.00 | .164 | 0.57 | 3.5 | 1.7 | 10.7 | 54.1 | 21 | 1 | 0 | 0 | 10 | 64 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1.24 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 77 | 11 | 0 | 2 | 3 | 0.38 | .156 | 0.56 | 3.6 | 1.4 | 6.0 | 72.0 | 29 | 3 | 3 | 1 | 11 | 48 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.31 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 89 | 22 | 0 | 8 | 2 | 0.11 | .118 | 0.40 | 2.4 | 1.2 | 5.0 | 166.2 | 44 | 2 | 2 | 0 | 23 | 93 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.30 |