| SP | Bauer, T.Bauer, Trevor >> | 29 | 2020 | R | 100 | 32 | 32 | 6 | 7 | 0.19 | .133 | 0.46 | 2.8 | 1.4 | 8.9 | 280.2 | 86 | 8 | 6 | 0 | 43 | 276 | 10 | 0 | 0 | 5 | 32 | 0 | 7 | 1.49 |
| SP | Smith, H.Smith, Hilton >> | 30 | 1937 | R | 96 | 33 | 32 | 6 | 4 | 0.23 | .130 | 0.44 | 3.0 | 0.9 | 5.2 | 280.0 | 94 | 9 | 7 | 0 | 29 | 162 | 3 | 0 | 0 | 3 | 32 | 2 | 2 | 2.18 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 96 | 98 | 0 | 1 | 2 | 0.00 | .129 | 0.45 | 2.5 | 1.6 | 11.8 | 51.2 | 14 | 2 | 0 | 0 | 9 | 67 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0.90 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 96 | 96 | 0 | 4 | 3 | 0.27 | .122 | 0.42 | 2.3 | 1.5 | 9.6 | 98.1 | 25 | 3 | 3 | 0 | 16 | 104 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 1.37 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 86 | 78 | 0 | 4 | 2 | 0.17 | .087 | 0.28 | 1.4 | 1.2 | 10.7 | 109.0 | 17 | 2 | 2 | 0 | 14 | 130 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 87 | 64 | 0 | 6 | 2 | 0.18 | .114 | 0.38 | 2.7 | 0.7 | 8.4 | 98.0 | 29 | 2 | 2 | 1 | 8 | 92 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1.53 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 82 | 56 | 0 | 2 | 1 | 0.18 | .143 | 0.49 | 2.7 | 1.7 | 6.5 | 100.0 | 30 | 2 | 2 | 0 | 19 | 72 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.16 |
| RP | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 80 | 41 | 0 | 4 | 1 | 0.26 | .153 | 0.54 | 3.0 | 1.9 | 9.5 | 70.0 | 23 | 2 | 2 | 0 | 15 | 74 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.53 |
| RP | Melancon, M.Melancon, Mark >> | 29 | 2014 | R | 72 | 53 | 0 | 6 | 3 | 0.65 | .158 | 0.55 | 3.6 | 1.4 | 6.7 | 83.2 | 33 | 6 | 6 | 2 | 13 | 62 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 2.33 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 80 | 23 | 0 | 4 | 11 | 0.58 | .144 | 0.50 | 3.4 | 1.0 | 5.6 | 155.0 | 59 | 13 | 10 | 0 | 18 | 96 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.13 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 87 | 29 | 6 | 3 | 7 | 0.50 | .173 | 0.61 | 4.5 | 1.0 | 5.1 | 198.2 | 99 | 12 | 11 | 1 | 23 | 112 | 3 | 1 | 0 | 0 | 6 | 3 | 2 | 2.33 |