| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 24 | 24 | 8 | 7 | 4.46 | .331 | 1.43 | 8.3 | 4.6 | 10.5 | 137.1 | 127 | 70 | 68 | 13 | 70 | 160 | 0 | 0 | 0 | 0 | 9 | 7 | 3 | 3.58 |
| SP | Mussina, M.Mussina, Mike # >> | 33 | 2001 | R | 68 | 23 | 23 | 6 | 12 | 4.49 | .299 | 1.25 | 9.1 | 2.2 | 9.2 | 150.1 | 152 | 75 | 75 | 20 | 36 | 153 | 1 | 0 | 0 | 0 | 14 | 4 | 1 | 3.49 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 51 | 23 | 23 | 8 | 8 | 4.61 | .332 | 1.46 | 10.1 | 3.0 | 7.4 | 158.0 | 178 | 86 | 81 | 24 | 53 | 130 | 1 | 0 | 0 | 1 | 9 | 5 | 8 | 4.43 |
| SP | Seo, J.Seo, Jae Weong # >> | 28 | 2005 | R | 48 | 23 | 23 | 5 | 13 | 5.83 | .346 | 1.55 | 11.4 | 2.5 | 5.4 | 139.0 | 176 | 95 | 90 | 28 | 39 | 84 | 1 | 0 | 0 | 0 | 7 | 6 | 5 | 5.38 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 64 | 0 | 5 | 4 | 3.58 | .305 | 1.30 | 8.0 | 3.7 | 9.7 | 88.0 | 78 | 36 | 35 | 11 | 36 | 95 | 0 | 2 | 6 | 0 | 0 | 2 | 4 | 3.76 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 58 | 0 | 0 | 7 | 4.50 | .288 | 1.19 | 7.1 | 3.6 | 6.7 | 74.0 | 58 | 42 | 37 | 9 | 30 | 55 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 4.39 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 52 | 54 | 0 | 5 | 1 | 4.11 | .295 | 1.22 | 7.5 | 3.5 | 7.8 | 61.1 | 51 | 28 | 28 | 7 | 24 | 53 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 4.03 |
| RP | Zumaya, J.Zumaya, Joel >> | 22 | 2006 | R | 37 | 33 | 0 | 2 | 3 | 6.39 | .370 | 1.71 | 9.7 | 5.7 | 9.5 | 38.0 | 41 | 28 | 27 | 6 | 24 | 40 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 5.00 |
| SP | Person, R.Person, Robert >> | 32 | 2001 | R | 26 | 14 | 0 | 2 | 2 | 6.93 | .383 | 1.86 | 11.6 | 5.6 | 5.6 | 24.2 | 31 | 22 | 19 | 4 | 15 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.79 |