| SP | Harden, R.Harden, Rich † # >> | 27 | 2008 | R | 95 | 30 | 30 | 17 | 8 | 2.41 | .265 | 1.08 | 6.5 | 3.2 | 9.6 | 202.0 | 147 | 55 | 54 | 12 | 71 | 216 | 1 | 0 | 0 | 1 | 21 | 0 | 3 | 2.69 |
| SP | Perez, O.Perez, Odalis >> | 25 | 2002 | L | 81 | 29 | 29 | 10 | 10 | 4.10 | .280 | 1.14 | 8.2 | 2.1 | 6.8 | 188.2 | 172 | 91 | 86 | 25 | 44 | 142 | 0 | 0 | 0 | 0 | 19 | 4 | 3 | 3.98 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 29 | 29 | 11 | 10 | 5.14 | .340 | 1.51 | 10.2 | 3.4 | 6.3 | 191.0 | 216 | 118 | 109 | 31 | 72 | 134 | 1 | 0 | 0 | 0 | 14 | 7 | 2 | 4.95 |
| SP | Garcia, F.Garcia, Freddy >> | 26 | 2001 | R | 61 | 28 | 28 | 11 | 11 | 5.45 | .351 | 1.58 | 10.0 | 4.2 | 6.0 | 195.0 | 216 | 126 | 118 | 40 | 92 | 129 | 3 | 0 | 0 | 1 | 11 | 8 | 3 | 5.88 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 96 | 81 | 0 | 6 | 1 | 2.44 | .235 | 0.89 | 6.3 | 1.7 | 9.0 | 121.2 | 85 | 34 | 33 | 10 | 23 | 121 | 0 | 9 | 4 | 0 | 0 | 4 | 3 | 2.74 |
| RP | Gordon, T.Gordon, Tom # >> | 37 | 2004 | R | 81 | 71 | 0 | 10 | 6 | 4.19 | .308 | 1.30 | 9.0 | 2.7 | 10.6 | 92.1 | 92 | 46 | 43 | 17 | 28 | 108 | 0 | 9 | 2 | 0 | 0 | 3 | 4 | 4.07 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 60 | 49 | 0 | 1 | 1 | 3.08 | .267 | 1.09 | 4.7 | 5.2 | 9.3 | 61.1 | 32 | 21 | 21 | 6 | 35 | 63 | 0 | 7 | 3 | 0 | 0 | 0 | 0 | 3.93 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 47 | 38 | 0 | 3 | 1 | 4.15 | .338 | 1.44 | 8.7 | 4.5 | 7.9 | 34.2 | 33 | 16 | 16 | 3 | 17 | 30 | 0 | 5 | 0 | 0 | 0 | 3 | 4 | 4.15 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 36 | 32 | 0 | 1 | 1 | 3.09 | .309 | 1.34 | 6.9 | 5.1 | 8.5 | 35.0 | 27 | 12 | 12 | 4 | 20 | 33 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.31 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 8 | 0 | 1 | 0 | 3.18 | .346 | 1.59 | 9.0 | 7.2 | 7.2 | 5.2 | 5 | 2 | 2 | 0 | 4 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.80 |