| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 15 | 15 | 7 | 4 | 2.97 | .253 | 0.99 | 6.1 | 2.8 | 9.5 | 115.1 | 78 | 38 | 38 | 15 | 36 | 122 | 3 | 0 | 0 | 1 | 11 | 3 | 3 | 3.59 |
| SP | Matsuzaka, D.Matsuzaka, Daisuke # >> | 28 | 2008 | R | 33 | 14 | 14 | 5 | 7 | 6.03 | .352 | 1.60 | 10.9 | 3.7 | 6.3 | 71.2 | 86 | 54 | 48 | 21 | 29 | 50 | 0 | 0 | 0 | 0 | 3 | 2 | 4 | 6.75 |
| SP | Person, R.Person, Robert >> | 31 | 2000 | R | 25 | 13 | 13 | 6 | 3 | 3.00 | .299 | 1.28 | 7.0 | 4.5 | 6.8 | 72.0 | 56 | 24 | 24 | 5 | 36 | 54 | 1 | 0 | 0 | 1 | 6 | 0 | 3 | 3.90 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 44 | 0 | 2 | 1 | 2.98 | .320 | 1.39 | 6.8 | 5.8 | 10.0 | 45.1 | 34 | 16 | 15 | 5 | 29 | 50 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.22 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 54 | 41 | 0 | 2 | 1 | 2.59 | .266 | 1.09 | 6.1 | 3.8 | 9.6 | 31.1 | 21 | 12 | 9 | 4 | 13 | 33 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 41 | 0 | 2 | 1 | 2.50 | .247 | 0.96 | 6.9 | 1.8 | 6.9 | 39.2 | 30 | 11 | 11 | 3 | 8 | 30 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.15 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 55 | 28 | 0 | 1 | 1 | 3.54 | .238 | 0.93 | 6.3 | 2.3 | 7.7 | 20.1 | 14 | 8 | 8 | 1 | 5 | 17 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.70 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 61 | 30 | 0 | 3 | 3 | 4.55 | .280 | 1.14 | 5.5 | 4.9 | 8.4 | 31.2 | 19 | 16 | 16 | 3 | 17 | 29 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 4.13 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 36 | 17 | 0 | 1 | 1 | 2.70 | .367 | 1.68 | 7.9 | 7.9 | 14.1 | 16.2 | 14 | 5 | 5 | 1 | 14 | 25 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.50 |